Comparative evaluation of evening primrose oil and vitamin E on the severity of cyclic Mastalgia: A Systematic Review and Meta-Analysis

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IRANI MORVARID; SHEIDAEI SEDIGHE; KHADIVZADEH TALAT; GHAZANFARPOUR MASOUMEH; Nosrati Seyedeh Fatemeh

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Journal: Iranian Journal of Obstetrics, Gynecology and Infertility Year:2020 | Volume:23 | Issue:3 Page(s): 91-98

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Title

Comparative evaluation of evening primrose oil and vitamin E on the severity of cyclic Mastalgia: A Systematic Review and Meta-Analysis

Author(s)

Keywords

Breast painQ2

Complementary medicineQ1

Evening primrose oilQ1

MastalgiaQ1

Meta-analysisQ1

Vitamin EQ2

Abstract

Introduction: Many women suffer from Mastalgia; this issue is very important due to the importance of proper use of the drug. Due to the complications of chemical drugs, patients tend to use Complementary medicine. Therefore, this systematic review was conducted with aim to compare the effects of Evening primrose oil and Vitamin E on cyclic Mastalgia. Methods: In this systematic review and Meta-analysis, data related to comparison of Evening primrose oil and Vitamin E were searched using the key words of Mastalgia, Evening primrose oil, Vitamin E, and Breast pain in the Electronic databases of Pubmed, Scopus, Web of science, Magiran, Iran doc, Iran medex, SID, and also Google scholar without time limitation until 2019. Jedad Index was used to evaluate the quality of the studies. Data were analyzed by Comprehensive Meta-analysis Version 2. Results: Among 701 articles found in the initial search, 8 randomized trials with sample volume of 878 participants were selected for this systematic review. The studies were conducted in U. S, India, Pakistan and Iran. The result of Meta-analysis showed that the difference between two groups of intervention and control was. 311 (95% CI:-0/266 to 0/888) and the difference was not statistically significant (p=0. 291); this indicates that the efficacy of Evening promise oil and Vitamin E is similar. Conclusion: The efficacy of Evening promise oil and Vitamin E in treatment of Mastalgia is similar. Given the high heterogeneity of studies, low sample size and the variety of methods for determining the outcome, further studies in this field is recommended.

Cites

Cyclic Mastalgia in Iranian Women: A Review

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APA: Copy

IRANI, MORVARID, SHEIDAEI, SEDIGHE, KHADIVZADEH, TALAT, GHAZANFARPOUR, MASOUMEH, & Nosrati, Seyedeh Fatemeh. (2020). Comparative evaluation of evening primrose oil and vitamin E on the severity of cyclic Mastalgia: A Systematic Review and Meta-Analysis. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, 23(3 ), 91-98. SID. https://sid.ir/paper/382975/en

Vancouver: Copy

IRANI MORVARID, SHEIDAEI SEDIGHE, KHADIVZADEH TALAT, GHAZANFARPOUR MASOUMEH, Nosrati Seyedeh Fatemeh. Comparative evaluation of evening primrose oil and vitamin E on the severity of cyclic Mastalgia: A Systematic Review and Meta-Analysis. IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY[Internet]. 2020;23(3 ):91-98. Available from: https://sid.ir/paper/382975/en

IEEE: Copy

MORVARID IRANI, SEDIGHE SHEIDAEI, TALAT KHADIVZADEH, MASOUMEH GHAZANFARPOUR, and Seyedeh Fatemeh Nosrati, “Comparative evaluation of evening primrose oil and vitamin E on the severity of cyclic Mastalgia: A Systematic Review and Meta-Analysis,” IRANIAN JOURNAL OF OBSTETRICS, GYNECOLOGY AND INFERTILITY, vol. 23, no. 3 , pp. 91–98, 2020, [Online]. Available: https://sid.ir/paper/382975/en

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