Effect of Oral Propranolol on Chest Pain in Pediatric Patients with Tricuspid Valve Regurgitation

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Asadpour Nabiollah; MALEKAHMADI MOHAMMAD REZA; GANJI FOROUZAN; Tahmasebi Shiva

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Journal: Jundishapur Scientific Medical Journal Year:2018 | Volume:17 | Issue:4 Page(s): 347-354

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Title

Effect of Oral Propranolol on Chest Pain in Pediatric Patients with Tricuspid Valve Regurgitation

Author(s)

Asadpour Nabiollah | MALEKAHMADI MOHAMMAD REZA | GANJI FOROUZAN | Tahmasebi Shiva | Issue Writer Certificate

Keywords

Chest painQ1

PropranololQ3

PediatricQ3

Tricuspid valve regurgitationQ1

Abstract

Background and Objectives: Chest pain is one of the major complications of Tricuspid valve regurgitation. Propranolol is a nonselective beta blocker that is commonly used to treat hypertension, irregular heartbeat, and cardiac pain and migraine headaches. The purpose of the present study was to evaluate the effect of oral Propranolol on Chest pain in children with Tricuspid valve regurgitation. Subjects and Methods: In this clinical trial, 38 children aged 5 to 16 y with a symptom of Chest pain due to moderate and severe Tricuspid valve regurgitation were randomly divided into two groups. The case group was treated with Propranolol 10 mg daily (0/5-1 mg/kg/d). Before and three months after the intervention, echocardiography was performed to assess the severity of Tricuspid valve regurgitation, cardiac output, systolic and diastolic pressure and pulmonary blood pressure. In addition, patients were questioned about the duration and frequency of Chest pain. Results: There was no significant difference between both groups in relation to the gender, residence location, associated heart disease and pain severity. Before intervention, pulmonary blood pressure, Tricuspid valve regurgitation and ejection fraction were not significantly different between intervention and control groups. Tricuspid valve regurgitation had a significant and positive correlation with pulmonary blood pressure (P<0. 001 and r = 0. 755). The response rate to treatment in the intervention group was 12 (63. 2%) and in the control group was 4 (21. 1%), which showed statistically significant difference. Conclusion: Propranolol significantly reduces Chest pain in children with Tricuspid valve regurgitation.

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APA: Copy

Asadpour, Nabiollah, MALEKAHMADI, MOHAMMAD REZA, GANJI, FOROUZAN, & Tahmasebi, Shiva. (2018). Effect of Oral Propranolol on Chest Pain in Pediatric Patients with Tricuspid Valve Regurgitation. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, 17(4 ), 347-354. SID. https://sid.ir/paper/383444/en

Vancouver: Copy

Asadpour Nabiollah, MALEKAHMADI MOHAMMAD REZA, GANJI FOROUZAN, Tahmasebi Shiva. Effect of Oral Propranolol on Chest Pain in Pediatric Patients with Tricuspid Valve Regurgitation. JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL[Internet]. 2018;17(4 ):347-354. Available from: https://sid.ir/paper/383444/en

IEEE: Copy

Nabiollah Asadpour, MOHAMMAD REZA MALEKAHMADI, FOROUZAN GANJI, and Shiva Tahmasebi, “Effect of Oral Propranolol on Chest Pain in Pediatric Patients with Tricuspid Valve Regurgitation,” JUNDISHAPUR SCIENTIFIC MEDICAL JOURNAL, vol. 17, no. 4 , pp. 347–354, 2018, [Online]. Available: https://sid.ir/paper/383444/en

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