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Information Journal Paper

Title

Antioxidants protective effects on oxidative stress damage induced by mycotoxins: A Review (review)

Pages

  1-20

Abstract

 Oxidative Stress identifies as the imbalance of Free radicals (reactive oxygen and nitrogen species) and Antioxidants defence. Cellular and tissue damage of Oxidative Stress causes enhances lipid peroxidation, DNA and protein damage and in finally cell death. Different exo/endogenous factors such as Mycotoxins play a role in causing damage mechanism with an increase or decrease the level of the vital molecule such as malondialdehyde (MDA) and glutathione (GSH). Mycotoxins are one of the most common foods and feed contaminants in the world, which considered a serious risk factor for human and animal health. Several enzymatic and/or nonenzymatic natural compounds with antioxidant activity could be inhibiting/reducing Oxidative Stress damage severity due to the free radical’ s imbalance via different mechanisms. The present study briefly reviews the Oxidative Stress of major Mycotoxins as a potential pathogenic mechanism, and the protective role of some natural plant and microbial compounds with antioxidant capacity (either separately or in combination) in reducing the adverse effects of the above stress. The use of natural and indigenous compounds with antioxidant properties in each region can be considered in the strategies for discovering and producing novel medicines and processed foods that have a protective/therapeutic role as one of the goals of green government establishment in macro-management policies in the country.

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    APA: Copy

    Afshar, Parvaneh, SHOKRZADEH, MOHAMMAD, ROOZBEH NASIRAIE, LEILA, Ghorbani HasanSaraei, Azade, Naghizadeh Raeisi, Shahram, & ALIMI, MAZDAK. (2020). Antioxidants protective effects on oxidative stress damage induced by mycotoxins: A Review (review). JOURNAL OF CLINICAL EXCELLENCE, 10(1 ), 1-20. SID. https://sid.ir/paper/384628/en

    Vancouver: Copy

    Afshar Parvaneh, SHOKRZADEH MOHAMMAD, ROOZBEH NASIRAIE LEILA, Ghorbani HasanSaraei Azade, Naghizadeh Raeisi Shahram, ALIMI MAZDAK. Antioxidants protective effects on oxidative stress damage induced by mycotoxins: A Review (review). JOURNAL OF CLINICAL EXCELLENCE[Internet]. 2020;10(1 ):1-20. Available from: https://sid.ir/paper/384628/en

    IEEE: Copy

    Parvaneh Afshar, MOHAMMAD SHOKRZADEH, LEILA ROOZBEH NASIRAIE, Azade Ghorbani HasanSaraei, Shahram Naghizadeh Raeisi, and MAZDAK ALIMI, “Antioxidants protective effects on oxidative stress damage induced by mycotoxins: A Review (review),” JOURNAL OF CLINICAL EXCELLENCE, vol. 10, no. 1 , pp. 1–20, 2020, [Online]. Available: https://sid.ir/paper/384628/en

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