Comparison of Outcomes of Incisional Infiltration with Lidocaine and Epinephrine Versus Lidocaine at the End of Cesarean Section Operation

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MOKHTARI MOJGAN; NEMATI MITRA; YAGHMAEI MINOO; Nazari Leila

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Journal: Research in Medicine Year:2020 | Volume:44 | Issue:3 Page(s): 473-478

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Information Journal Paper

Title

Comparison of Outcomes of Incisional Infiltration with Lidocaine and Epinephrine Versus Lidocaine at the End of Cesarean Section Operation

Author(s)

MOKHTARI MOJGAN | NEMATI MITRA | YAGHMAEI MINOO | Nazari Leila | Issue Writer Certificate

Keywords

Cesarean SectionQ3

PainQ3

PostoperativeQ1

Surgical WoundQ2

LidocaineQ3

EpinephrineQ3

Abstract

Background: Postoperative Pain is an important clinical issue. Since post-cesarean Pain can affect maternal and neonatal health, the present study was conducted to compare the effects of Lidocaine and Epinephrine infiltration with Lidocaine alone at the site of incision at the end of Cesarean Section. Materials and Methods: The current study was performed on 100 women with term pregnancies who were candidate for elective cesarean with spinal anesthesia. Patients were randomly divided into two groups of 20 ml %2 Lidocaine or 20 ml solution of 4/1 of 1 mg/ml Epinephrine in 50cc of %2 Lidocaine (200000/1 dilution) infiltrated subcutaneously after cesarean and before closing the skin. Measurement of Pain and narcotic use after surgery, the time of first lactating, the time of getting out of bed, and discharge time were compared between the two groups using statistical tests, independent t, fisher exact test, and chi-square. Findings: Individuals who were infused with Lidocaine and Epinephrine at the end of the Cesarean Section at the time of incision initiated breastfeeding earlier (P = 0. 018) and were discharged earlier (P = 0. 010) than those receiving Lidocaine alone. Also, the first group had less Pain intensity from four hours Postoperatively until the end of the first day Postoperatively (P <0. 001) and their pethidine consumption was lower (P <0. 001). Conclusion: It seems that adding Epinephrine to the local anesthetics like Lidocaine can prolong the effect of anesthetics, reduce the doses of narcotic use after surgery, and decrease the time of first lactating and discharge from hospital.

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References

Intraperitoneal Instillation of Lidocaine Improves Postoperative Analgesia at Cesarean Delivery

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APA: Copy

MOKHTARI, MOJGAN, NEMATI, MITRA, YAGHMAEI, MINOO, & Nazari, Leila. (2020). Comparison of Outcomes of Incisional Infiltration with Lidocaine and Epinephrine Versus Lidocaine at the End of Cesarean Section Operation. PAJOUHESH DAR PEZESHKI, 44(3 ), 473-478. SID. https://sid.ir/paper/392553/en

Vancouver: Copy

MOKHTARI MOJGAN, NEMATI MITRA, YAGHMAEI MINOO, Nazari Leila. Comparison of Outcomes of Incisional Infiltration with Lidocaine and Epinephrine Versus Lidocaine at the End of Cesarean Section Operation. PAJOUHESH DAR PEZESHKI[Internet]. 2020;44(3 ):473-478. Available from: https://sid.ir/paper/392553/en

IEEE: Copy

MOJGAN MOKHTARI, MITRA NEMATI, MINOO YAGHMAEI, and Leila Nazari, “Comparison of Outcomes of Incisional Infiltration with Lidocaine and Epinephrine Versus Lidocaine at the End of Cesarean Section Operation,” PAJOUHESH DAR PEZESHKI, vol. 44, no. 3 , pp. 473–478, 2020, [Online]. Available: https://sid.ir/paper/392553/en

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