A STUDY OF SERUM Β2 MICROGLOBULIN (SΒ2M) IN HEMODIALYSIS PATIENTS WITH CELLULOSIS MEMBRANE

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MIRAHMADIAN M.; REZAEI S.A.R.; NIKBIN B.

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Journal: Tehran University Medical Journal Year:2000 | Volume:58 | Issue:2 Page(s): 66-70

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Title

A STUDY OF SERUM Β2 MICROGLOBULIN (SΒ2M) IN HEMODIALYSIS PATIENTS WITH CELLULOSIS MEMBRANE

Author(s)

MIRAHMADIAN M. | REZAEI S.A.R. | NIKBIN B. | Issue Writer Certificate

Keywords

Β2 MICROGLOBULINQ4

HEMODIALYSISQ4

DIALYSIS MEMBRANESQ4

CELLULOSIS MEMBRANESQ4

AMYLOIDOSISQ4

Abstract

Β2 MICROGLOBULIN (β2M) fibril has been rccognizell as the major factor of dialysis -related AMYLOIDOSIS.Elevated serum levels are thought to be the basis for tissue deposition.In order to evaluate the effect of cellulosis membrane (FB 110) and treatment duration on Sβ2M levels, we determined serum levels in 23 hemodialyzed patients with end - stage renal failure. Sβ2M levels were markedly elevated in all patients with a mean of 74.71 (SD=21.2 mg/l, range: 46 mg/l after 2 years HEMODIALYSIS - 123.8 mg/l after 10 years treatment) that statistically is higher than healthy subjects (P<0.0001). Serum β2M in 19 healthy subjects was 2.36 (SD=0,4 mg/l, rang: 1.58-33 mg/).Although in HEMODIALYSIS group, no significant correlation was found between Sβ2M and age or sex but increased serum levels of β2M had significant correlation with duration of HEMODIALYSIS treatment (r = 0.53, P<0.01).Since the dialysis membrane has a very effective role in clearancce of Sβ2M,we suggest that the particular effort shoud be made twords improvement of diaslysis membranes.

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APA: Copy

MIRAHMADIAN, M., REZAEI, S.A.R., & NIKBIN, B.. (2000). A STUDY OF SERUM Β2 MICROGLOBULIN (SΒ2M) IN HEMODIALYSIS PATIENTS WITH CELLULOSIS MEMBRANE. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 58(2), 66-70. SID. https://sid.ir/paper/39323/en

Vancouver: Copy

MIRAHMADIAN M., REZAEI S.A.R., NIKBIN B.. A STUDY OF SERUM Β2 MICROGLOBULIN (SΒ2M) IN HEMODIALYSIS PATIENTS WITH CELLULOSIS MEMBRANE. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2000;58(2):66-70. Available from: https://sid.ir/paper/39323/en

IEEE: Copy

M. MIRAHMADIAN, S.A.R. REZAEI, and B. NIKBIN, “A STUDY OF SERUM Β2 MICROGLOBULIN (SΒ2M) IN HEMODIALYSIS PATIENTS WITH CELLULOSIS MEMBRANE,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 58, no. 2, pp. 66–70, 2000, [Online]. Available: https://sid.ir/paper/39323/en

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