A SURVEY ON THE EFFECT OF LOVASTATIN AND EXERCISE ON SERUM LIPID PROFILES IN HYPERLIPIDEMIC PATIENTS

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TAGHADOSI M.; SEYEDI M.; MOUSAVI SEYED GHOLAM ABAS; FATHGHARIB J.

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Journal: Feyz Medical Sciences Journal Year:2009 | Volume:13 | Issue:3 (SERIAL 51) Page(s): 188-194

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Title

A SURVEY ON THE EFFECT OF LOVASTATIN AND EXERCISE ON SERUM LIPID PROFILES IN HYPERLIPIDEMIC PATIENTS

Author(s)

TAGHADOSI M. | SEYEDI M. | MOUSAVI SEYED GHOLAM ABAS | FATHGHARIB J. | Issue Writer Certificate

Keywords

HYPERLIPIDEMIAQ2

LOVASTATINQ2

EXERCISEQ2

CHOLESTEROLQ3

TRIGLYCERIDESQ3

Abstract

Background: High lipid serum level was a risk factor for cardiovascular disease. This study was performed to evaluate the effects of LOVASTATIN and EXERCISE on hyperlipidemic patients at Kashan Shahid Beheshti Hospital during 2005–6.Materials and Methods: This randomized clinical trial study was carried out on hyperlipidemic patients (age>30 years). After registering the personal data of the patients the participants were selected based on the inclusion criteria (HDL<35 mg/dl, LDL³160 mg/dl, TG³200 mg/dl, Chol³200 mg/dl). the LOVASTATIN group (40 mg/daily) and the EXERCISE group (waking 35 minutes/day, 3 times a week). The clinical tests were repeated for six consecutive weeks. Data were analyzed using t-Test, Wilcoxon Signed Rample Test, Kolomogorou-Smirnov Test, Mann-Whitney Test, levens Test. Results: from Ninety-six out of 150 cases were hyperlipidmic signifying that only 80 (59 male, mean age 55.12±8.4 case and control 55.35±9.2 years) out of 150 hyperlipidemic patients were qualified for the study. The mean decrease in TG level between the LOVASTATIN and EXERCISE groups were 21.4 (P=0.2) and 20.5 mg/dl (P=0.2), respectively. The mean decrease in CHOLESTEROL level between LOVASTATIN and EXERCISE groups were 41.3 and 1.5 mg/dL (P=0.001). The mean decrease in LDL level between LOVASTATIN and EXERCISE groups were 35.8 and 8.5 mg/dl (P<0.001), respectively. Finally, the mean increase in HDL level between LOVASTATIN and EXERCISE groups was 5.4 and 0.4 mg/dl.Conclusion: EXERCISE may be effective for decreasing the LDL. While LOVASTATIN could decrease the total CHOLESTEROL TG and increase HDL levels, using a combination is recommended for hyperlipidemic patients.

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APA: Copy

TAGHADOSI, M., SEYEDI, M., MOUSAVI, SEYED GHOLAM ABAS, & FATHGHARIB, J.. (2009). A SURVEY ON THE EFFECT OF LOVASTATIN AND EXERCISE ON SERUM LIPID PROFILES IN HYPERLIPIDEMIC PATIENTS. FEYZ, 13(3 (SERIAL 51)), 188-194. SID. https://sid.ir/paper/393857/en

Vancouver: Copy

TAGHADOSI M., SEYEDI M., MOUSAVI SEYED GHOLAM ABAS, FATHGHARIB J.. A SURVEY ON THE EFFECT OF LOVASTATIN AND EXERCISE ON SERUM LIPID PROFILES IN HYPERLIPIDEMIC PATIENTS. FEYZ[Internet]. 2009;13(3 (SERIAL 51)):188-194. Available from: https://sid.ir/paper/393857/en

IEEE: Copy

M. TAGHADOSI, M. SEYEDI, SEYED GHOLAM ABAS MOUSAVI, and J. FATHGHARIB, “A SURVEY ON THE EFFECT OF LOVASTATIN AND EXERCISE ON SERUM LIPID PROFILES IN HYPERLIPIDEMIC PATIENTS,” FEYZ, vol. 13, no. 3 (SERIAL 51), pp. 188–194, 2009, [Online]. Available: https://sid.ir/paper/393857/en

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