THE ASSOCIATION BETWEEN GSTP1 A/G POLYMORPHISM AND OXIDATIVE STRESS WITH END STAGE RENAL DISEASE IN KERMANSHAH

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NOMANI H.; AIDY A.; HAGH NAZARI L.; REISSI D.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ) Year:2013 | Volume:16 | Issue:9 (78) Page(s): 0-0

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

687

Download:

Cites:

Information Journal Paper

Title

THE ASSOCIATION BETWEEN GSTP1 A/G POLYMORPHISM AND OXIDATIVE STRESS WITH END STAGE RENAL DISEASE IN KERMANSHAH

Author(s)

NOMANI H. | AIDY A. | HAGH NAZARI L. | REISSI D. | Issue Writer Certificate

Keywords

END STAGE RENAL DISEASEQ2

GLUTATHIONE S TRANSFERASE PQ2

HPLCQ2

MALONDIALDEHYDEQ2

Abstract

Background: In end stage of renal disease (ESRD), renal function deteriorates progressively and irreversibly in which the body’s ability to maintain metabolic, fluid and electrolyte balance fails. Glutathione s-transferase P1 is a member of multigene family that plays an essential role as an important antioxidant in cells. In this study we investigated the polymorphism of GSTP1 genotypes and oxidative stress in ESRD patients compared with control subjects to determine the possible relation between polymorphism of this enzyme and ESRD.Material and Methods: In this case-control study, 136 ESRD patients and 137 healthy cases (without kidney disease) were selected and GST P1 polymorphism was determined with PCR-RFLP. Level of MDA was measured by HPLC apparatus.Results: Genotypes distribution of GSTP1 A/G polymorphism to AA, AG and GG genotypes in control group were respectively 70 (51.1%), 56 (40.9%) and 11 (8%) and in ESRD group were 74 (55.6%), 50 (37.6%) and 9 (6.8%), respectively (p=0.744). MDA levels in ESRD patients were higher than control group (p<0.001).Conclusion: GSTP1 A/G polymorphism between two groups and each groups was not statistically significant with ESRD, probably this enzyme has a protective role in the risk of ESRD.

Cites

THE EFFECTS OF VITAMIN D SUPPLEMENTATION ON THE ANTIOXIDANT SERUM LEVEL IN 6-13 YEARS OLD CHILDREN WITH ADHD

References

No record.

Cite

APA: Copy

NOMANI, H., AIDY, A., HAGH NAZARI, L., & REISSI, D.. (2013). THE ASSOCIATION BETWEEN GSTP1 A/G POLYMORPHISM AND OXIDATIVE STRESS WITH END STAGE RENAL DISEASE IN KERMANSHAH. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 16(9 (78)), 0-0. SID. https://sid.ir/paper/395189/en

Vancouver: Copy

NOMANI H., AIDY A., HAGH NAZARI L., REISSI D.. THE ASSOCIATION BETWEEN GSTP1 A/G POLYMORPHISM AND OXIDATIVE STRESS WITH END STAGE RENAL DISEASE IN KERMANSHAH. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2013;16(9 (78)):0-0. Available from: https://sid.ir/paper/395189/en

IEEE: Copy

H. NOMANI, A. AIDY, L. HAGH NAZARI, and D. REISSI, “THE ASSOCIATION BETWEEN GSTP1 A/G POLYMORPHISM AND OXIDATIVE STRESS WITH END STAGE RENAL DISEASE IN KERMANSHAH,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 16, no. 9 (78), pp. 0–0, 2013, [Online]. Available: https://sid.ir/paper/395189/en

Related Journal Papers