AN OVERVIEW OF NANOPARTICLES AND THEIR APPLICATIONTO DRUG DELIVERY IN CANCER: REVIEW ARTICLE

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NASERIAN FARZANEH; HESHMATI FATEME; MEHDIZADEH OMRANI MARYAM; Salarian Reza

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Paper Information

Journal: TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ) Year:2018 | Volume:76 | Issue:4 Page(s): 221-230

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Title

AN OVERVIEW OF NANOPARTICLES AND THEIR APPLICATIONTO DRUG DELIVERY IN CANCER: REVIEW ARTICLE

Author(s)

NASERIAN FARZANEH | HESHMATI FATEME | MEHDIZADEH OMRANI MARYAM | Salarian Reza | Issue Writer Certificate

Keywords

DISEASEQ1

DRUG DELIVERY SYSTEMSQ1

NANOPARTICLESQ1

POLYMERSQ1

Abstract

Today, nanoscience has grown and developed in various medical and therapeuticareas, including cancer treatment. On the other hand, cancer and its types have beenrumored and inclusive and many people suffer from this fatal and deadly DISEASE. Currently, existing therapeutic method, including chemotherapy, radiotherapy, andetc., along with the therapeutic effect, cause complications that are unpleasant forpatients. Hence, scientists and researchers are looking to develop and improvetreatment options and methods to deal with this serious DISEASE. Today, nanoscienceand nanotechnology have become widespread, and its various fields, includingnanoparticles, are widely used for a variety of applications, especially for delivery ofdrugs and diagnostic items and imaging cases. Nanotechnology-based releasesystems have a significant impact on the release of cancer drugs. Advances in biomaterialsand bio-engineering are contributing to new approaches to NANOPARTICLESthat may create a new way for the improvement of cancer patients. Nano-technologyin the drug release system has had a great impact on the selection of cancer cells, therelease of a targeted drug, and overcoming the limitations of conventionalchemotherapy. At the present many DRUG DELIVERY SYSTEMS are now made ofnanoparticles, and various substances have been used as drug-stimulating agents oras a reinforcing agent to improve the efficacy of the treatment and durability andstability and also the safety of anticancer drugs. The materials used to release cancerdrugs are divided into various categories such as polymer, magnetic, biomolecules. In the meantime, polymer NANOPARTICLES have been organized in the carriers of anticancernanoparticles due to the process of easy production, biocompatibility, andbiodegradability. Although the loading of hydrophilic compounds is still confrontedwith limitations, due to the diversity of nanoparticle structures, it is possible toencapsulate various molecules. Also, surface changes and modification such asbinding to antibodies and target ligands can also be applied to these materials, to actas target drug delivery to increase the effectiveness of treatment process. In thisarticle, we will have an overview of cancer DISEASE and cancer drugs and alsonanoparticles and their contribution to cancer treatment.

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References

Potential 5-fluorouracil encapsulated mPEG-Chitosan nanogels for controlling drug release

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APA: Copy

NASERIAN, FARZANEH, HESHMATI, FATEME, MEHDIZADEH OMRANI, MARYAM, & Salarian, Reza. (2018). AN OVERVIEW OF NANOPARTICLES AND THEIR APPLICATIONTO DRUG DELIVERY IN CANCER: REVIEW ARTICLE. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 76(4 ), 221-230. SID. https://sid.ir/paper/39623/en

Vancouver: Copy

NASERIAN FARZANEH, HESHMATI FATEME, MEHDIZADEH OMRANI MARYAM, Salarian Reza. AN OVERVIEW OF NANOPARTICLES AND THEIR APPLICATIONTO DRUG DELIVERY IN CANCER: REVIEW ARTICLE. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2018;76(4 ):221-230. Available from: https://sid.ir/paper/39623/en

IEEE: Copy

FARZANEH NASERIAN, FATEME HESHMATI, MARYAM MEHDIZADEH OMRANI, and Reza Salarian, “AN OVERVIEW OF NANOPARTICLES AND THEIR APPLICATIONTO DRUG DELIVERY IN CANCER: REVIEW ARTICLE,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 76, no. 4 , pp. 221–230, 2018, [Online]. Available: https://sid.ir/paper/39623/en

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