Prevalancy of cagA and babA of Helicobacter pylori isolated from gastric atrophic patients

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Safarnejad Sekineh; TALEBI BEZMIN ABADI AMIN

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Journal: Journal of Gorgan University of Medical Sciences Year:2020 | Volume:22 | Issue:1 (73) Page(s): 82-87

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Title

Prevalancy of cagA and babA of Helicobacter pylori isolated from gastric atrophic patients

Author(s)

Safarnejad Sekineh | TALEBI BEZMIN ABADI AMIN | Issue Writer Certificate

Keywords

Helicobacter pyloriQ3

cagAQ1

babAQ1

Gastric cancerQ2

Gastric atrophyQ2

Abstract

Background and Objective: The infection of Helicobacter pylori (H. pylori) is one of the most complex items addressed in the clinical microbiology. Although H. pylori positive subjects are bound to develop into atrophic gastritis, current body of evidences is rare. Due to the high prevalence of this bacterium worldwide, finding the true virulence factors as biomarkers for severe gastroduodenal diseases was the priority in recent researches. This study was carried out to determine the prevalancy of cagA and babA of Helicobacter pylori isolated from gastric atrophic patients. Methods: This descriptive – analytical study was conducted on 100 patients with gastroduodenal disorders in Labafinejad hospital in Tehran, Iran during 2018. Identification of each patient and also bacterial isolation were undertaken according to the standard protocols. Results: H. pylori were isolated in 23% of patients. 10 patients affected by atrophic gastritis followd by gastric ulcer (7 patients) and acute gastritis (6 patients). In totally, the rate of cagA gene and babA in H. pylori isolated with positive results was 52% and 34%, respectively. There was a significant association between the presence of cagA positive strains and patients with gastric atrophic (P<0. 05). The babA gene did not correlate with the presence of gastric atrophic patients. Conclusion: This study showed that various carrying cagA positive H. pylori can be recovered from patients with Gastric atrophy.

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APA: Copy

Safarnejad, Sekineh, & TALEBI BEZMIN ABADI, AMIN. (2020). Prevalancy of cagA and babA of Helicobacter pylori isolated from gastric atrophic patients. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 22(1 (73) ), 82-87. SID. https://sid.ir/paper/397086/en

Vancouver: Copy

Safarnejad Sekineh, TALEBI BEZMIN ABADI AMIN. Prevalancy of cagA and babA of Helicobacter pylori isolated from gastric atrophic patients. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;22(1 (73) ):82-87. Available from: https://sid.ir/paper/397086/en

IEEE: Copy

Sekineh Safarnejad, and AMIN TALEBI BEZMIN ABADI, “Prevalancy of cagA and babA of Helicobacter pylori isolated from gastric atrophic patients,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 22, no. 1 (73) , pp. 82–87, 2020, [Online]. Available: https://sid.ir/paper/397086/en

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