The Effect of 8-Weeks of Low-Intensity Swimming Training on Promyelocytic Leukemia Zinc Finger Protein and Spermatid Transition Nuclear Protein Gene Expression in Azoospermic Rats Model

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Zohrabi Karani Leila; FARZANEGI PARVIN; AZARBAYJANI MOHAMAD ALI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Internal Medicine Today Year:2020 | Volume:26 | Issue:4 Page(s): 332-347

Download Full-Text

Persian Verion

View:

196

Download:

177

Cites:

Information Journal Paper

Title

The Effect of 8-Weeks of Low-Intensity Swimming Training on Promyelocytic Leukemia Zinc Finger Protein and Spermatid Transition Nuclear Protein Gene Expression in Azoospermic Rats Model

Author(s)

Zohrabi Karani Leila | FARZANEGI PARVIN | AZARBAYJANI MOHAMAD ALI | Issue Writer Certificate

Keywords

SwimmingQ1

Promyelocytic Leukemia Zinc Finger (PLZF) proteinQ1

Spermatid Transition Nuclear Protein (TNP)Q1

AzoospermiaQ2

Abstract

Aims: One of the causes of infertility in men is the Azoospermia disease, which is attributed to the lack of sperm in each sperm. The primary function of spermatogenesis is the maintenance, proliferation, and differentiation of spermatogonial cells. Thus, the present study aimed to investigate the changes in Promyelocytic Leukemia Zinc Finger (PLZF) and spermatid Transition Nuclear Protein (TNP) gene expression levels in an azoospermic rat model after 8 weeks of low-intensity aerobic training. Methods & Materials: In this experimental study, 15 adult male Wistar rats were randomly divided into three groups of healthy control, with Azoospermia, and exercise plus Azoospermia after creating an Azoospermia model. The patient plus exercise group performed a low-intensity Swimming exercise 30 minutes a day, five days a week for 8 weeks, after the creation of the azoospermic rats. A One-way ANOVA test was used for data analysis. Findings: The results showed that a period of Swimming exercise program in the exercise plus Azoospermia group significantly reduced PLZF gene expression compared to the healthy control groups (P=0. 001) and no significant increase to the Azoospermia group (P=0. 06). There was also a significant decrease in TNP gene expression levels in the exercise plus Azoospermia group compared to the healthy control group (P=0. 001) and a significant increase in the Azoospermia group (P=0. 057). Conclusion: Based on these Findings, it can be stated that the alteration of key molecules or signaling pathways and expression of the PLZF and TNP genes in the spermatogenesis process may increase infertility, but regular aerobic exercise, such as low-intensity Swimming, helps to control the effects of infertility by increasing the maintenance and development of spermatogonial stem cells.

Cites

No record.

References

Cite

APA: Copy

Zohrabi Karani, Leila, FARZANEGI, PARVIN, & AZARBAYJANI, MOHAMAD ALI. (2020). The Effect of 8-Weeks of Low-Intensity Swimming Training on Promyelocytic Leukemia Zinc Finger Protein and Spermatid Transition Nuclear Protein Gene Expression in Azoospermic Rats Model. OFOGH-E-DANESH, 26(4 ), 332-347. SID. https://sid.ir/paper/397394/en

Vancouver: Copy

Zohrabi Karani Leila, FARZANEGI PARVIN, AZARBAYJANI MOHAMAD ALI. The Effect of 8-Weeks of Low-Intensity Swimming Training on Promyelocytic Leukemia Zinc Finger Protein and Spermatid Transition Nuclear Protein Gene Expression in Azoospermic Rats Model. OFOGH-E-DANESH[Internet]. 2020;26(4 ):332-347. Available from: https://sid.ir/paper/397394/en

IEEE: Copy

Leila Zohrabi Karani, PARVIN FARZANEGI, and MOHAMAD ALI AZARBAYJANI, “The Effect of 8-Weeks of Low-Intensity Swimming Training on Promyelocytic Leukemia Zinc Finger Protein and Spermatid Transition Nuclear Protein Gene Expression in Azoospermic Rats Model,” OFOGH-E-DANESH, vol. 26, no. 4 , pp. 332–347, 2020, [Online]. Available: https://sid.ir/paper/397394/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops