Effect of 6 weeks aerobic exercise and oral Royal Jelly consumption on inflammatory factors' multiple sclerosis patients

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Molaei Rahmatollah; VAHIDIAN REZAZADEH MAJID; MOGHTADERI ALI

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Journal: MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES Year:2019 | Volume:62 | Issue:3 Page(s): 1524-1532

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Title

Effect of 6 weeks aerobic exercise and oral Royal Jelly consumption on inflammatory factors' multiple sclerosis patients

Author(s)

Molaei Rahmatollah | VAHIDIAN REZAZADEH MAJID | MOGHTADERI ALI | Issue Writer Certificate

Keywords

Aerobic ExerciseQ1

Royal JellyQ2

TNF-alphaQ1

C-reactive proteinQ1

NeutrophilQ2

Multiple SclerosisQ2

Abstract

Introduction: MS pathogenesis involves inflammation and the phase of nerve degeneration. MS begins with an autoimmune inflammation of the myelin sheath and often with a sudden attack. Then enter the recovery phase, which lasts a few months to several years. The present study was conducted to evaluate six weeks Aerobic Exercise and Royal Jelly consumption on inflammatory factors TNF-α , hs-CRP and Neutrophil in MS patients. Materials and Methods: Overall 42 MS patients participated in this quasiexperimental study. The subjects were randomly selected and divided into 4 groups: 1-exercise + Royal Jelly (n=10), 2-exercise + placebo (n=10), 3-Royal Jelly (n=11) and 4-Placebo (n=11). The exercise was performed for 6 weeks, 3 sessions per week on the ergometer and intensity of 60% HRmax. Then, it gradually increased and sixth week reached 80% HRmax. The daily dose of Royal Jelly was 1000 mg. Plasma concentrations of inflammatory factors were measured before and after the study. Results: The results showed a significant decrease in TNF-α of exercise+Royal Jelly (P=0. 039), exercise+Placebo (P=0. 049) and Royal Jelly (P=0. 015) groups; However, there was no significant difference in Placebo group (P=0. 364). There was a significant difference between hs-CRP exercise+Royal Jelly (P=0. 002), exercise+placebo (P=0. 047) and Royal Jelly (P=0. 042). There was observed a significant decrease in Neutrophil levels of exercise+Royal Jelly (P=0. 028) and placebo (P=0. 1010). This was not significant in Royal Jelly (P=0. 252) and placebo (P=0. 336) groups. Conclusion: The results of this study showed that Aerobic Exercise and Royal Jelly consumption improve TNF-α , hs-CRP, and Neutrophil in MS patients.

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APA: Copy

Molaei, Rahmatollah, VAHIDIAN REZAZADEH, MAJID, & MOGHTADERI, ALI. (2019). Effect of 6 weeks aerobic exercise and oral Royal Jelly consumption on inflammatory factors' multiple sclerosis patients. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 62(3 ), 1524-1532. SID. https://sid.ir/paper/397942/en

Vancouver: Copy

Molaei Rahmatollah, VAHIDIAN REZAZADEH MAJID, MOGHTADERI ALI. Effect of 6 weeks aerobic exercise and oral Royal Jelly consumption on inflammatory factors' multiple sclerosis patients. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;62(3 ):1524-1532. Available from: https://sid.ir/paper/397942/en

IEEE: Copy

Rahmatollah Molaei, MAJID VAHIDIAN REZAZADEH, and ALI MOGHTADERI, “Effect of 6 weeks aerobic exercise and oral Royal Jelly consumption on inflammatory factors' multiple sclerosis patients,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 62, no. 3 , pp. 1524–1532, 2019, [Online]. Available: https://sid.ir/paper/397942/en

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