EFFICACY OF CELECOXIB ON NOCTURIA IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FALAHATKAR S.; MOKHTARI GH.R.; ASGHARI S.A.A.D.; NOUSHAD KAMRAN A.R.; NIKPOUR SARA; AKBARPOUR M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES Year:2008 | Volume:16 | Issue:64 Page(s): 1-7

Download Full-Text

Persian Verion

View:

1,892

Download:

Cites:

Information Journal Paper

Title

EFFICACY OF CELECOXIB ON NOCTURIA IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA

Author(s)

Keywords

CELECOXIBQ3

NOCTURIAQ3

PROSTATIC HYPERPLASIAQ3

Abstract

Introduction: Benign PROSTATIC HYPERPLASIA is a pathologic process and main reason for lower urinary tract symptoms in old men. Its most common sign is NOCTURIA. BPH treatment has relative response to al-blockers and 5- a reductase Inhibitors (25-39%). CELECOXIB is used as a cyclooxygenase II allocated inhibitor, low price, available drug and could be effective in decreasing the incidence of NOCTURIA.Objective: Survey efficacy of CELECOXIB on NOCTURIA in patients with Benign PROSTATIC HYPERPLASIA.Materials and Methods: In this clinical trial study, among patients with LUTS suggestive of BPH, 40 men those had IPSS score³8 and prostate volume³20cm2 were, enrolled. These patients had NOCTURIA³2 despite previous standard medical treatment. Patients underwent primary urotlowmetry and received 100mg CELECOXIB at 9pm every night along with previous treatment for I month. Reevaluation of disease with second urotlowmetry and determining incidence of NOCTURIA after treatment was performed. Statistical analysis was done by chi-square test, simple Hest, and pair t-test and krusskal-wallis test.Results: Forty patients with mean age of 64.3±7.7 years were studies, mean prostate size of them was 41.8±13.2 cm2, initial mean IPSS score was 18.2±3.4 and initial mean Qmax was 12.5±2.5ml/s. 95% of patients complained NOCTURIA twice at night. After receiving 100 mgCELECOXIB during I month, Range of received answers were appraised. The effects after treatment were assessed: excellent reaction (nocturia disappeared or decreased by 2 or more voids/night), improved reaction (nocturia decreased by 1 void/night) and unchanged reaction, obtained in 70%, 12.5% and 17.5% in patients, respectively. Mean frequency of NOCTURIA decreased from 5.17±2.1before treatment to 2.5±1.9 after it (P<0.0001), Mean IPSS score and Mean Qmax of patients after treatment were 15.5±4.2 (P<0.0001) and 12.9±2.7ml/s (P=0.05) respectively.Conclusions: Improved or disappeared NOCTURIA is 82.5% in patients. The results of our study advise to use CELECOXIB in combination with standard medical therapy for BPH as a useful alternative treatment.

Cites

No record.

References

No record.

Cite

APA: Copy

FALAHATKAR, S., MOKHTARI, GH.R., ASGHARI, S.A.A.D., NOUSHAD KAMRAN, A.R., NIKPOUR, SARA, & AKBARPOUR, M.. (2008). EFFICACY OF CELECOXIB ON NOCTURIA IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA. JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, 16(64), 1-7. SID. https://sid.ir/paper/39838/en

Vancouver: Copy

FALAHATKAR S., MOKHTARI GH.R., ASGHARI S.A.A.D., NOUSHAD KAMRAN A.R., NIKPOUR SARA, AKBARPOUR M.. EFFICACY OF CELECOXIB ON NOCTURIA IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA. JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2008;16(64):1-7. Available from: https://sid.ir/paper/39838/en

IEEE: Copy

S. FALAHATKAR, GH.R. MOKHTARI, S.A.A.D. ASGHARI, A.R. NOUSHAD KAMRAN, SARA NIKPOUR, and M. AKBARPOUR, “EFFICACY OF CELECOXIB ON NOCTURIA IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA,” JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, vol. 16, no. 64, pp. 1–7, 2008, [Online]. Available: https://sid.ir/paper/39838/en

Related Journal Papers