THE FIRST SURVEY OF DISTRIBUTION OF INHERITED DEAFNESS PATTERNS IN INDIVIDUALS REFERRED TO GENETIC CENTER OF AHVAZ WELFARE ORGANIZATION, SOUTHERN IRAN

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FOROUGHMAND ALI MOHAMMAD; GALEHDARI HAMID; MOHAMMADIAN GHOLAMREZA; RASEKH ABDOLRAHMAN; GHAVABESH JASEM

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Journal: Auditory and Vestibular Research Journal Year:2011 | Volume:20 | Issue:2 (36) Page(s): 73-78

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Title

THE FIRST SURVEY OF DISTRIBUTION OF INHERITED DEAFNESS PATTERNS IN INDIVIDUALS REFERRED TO GENETIC CENTER OF AHVAZ WELFARE ORGANIZATION, SOUTHERN IRAN

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Keywords

SYNDROMIC DEAFNESSQ2

NON-SYNDROMIC DEAFNESSQ2

INHERITANCE PATTERNSQ2

CONSANGUINEOUS MARRIAGESQ2

ARABQ2

NON-ARAB POPULATIONQ2

Abstract

Background and Aim: Deafness is a heterogeneous disorder induced by genetic and environmental factors. It is the most common hereditary sensory-neural disorder that affects 1/1000 to 1/2000 of the newborns. More than 70% of hearing loss cases are caused by genetic disorders, 85% of which result from nonsyndromic autosomal recessive sensory-neural hearing loss. Up to now, more than 100 genes contributing in hearing loss have been determined. Alteration of these genes may result in hearing loss.This study was performed to identify the INHERITANCE PATTERNS of deafness and its relation with ethnicity, gender and CONSANGUINEOUS MARRIAGES.Methods: In this survey, data from 356 families affected by hearing loss and referred to welfare organization of Ahvaz during the time were collected based on sex, ethnic groups and relativeness.Results: The results state a high frequency of autosomal recessive deafness caused by CONSANGUINEOUS MARRIAGES within ARAB and non-Arab ethnic groups (p<0.05). But no significant difference in gender.Conclusion: In conclusion, the high frequency of autosomal recessive deafness among the population with a high frequency of CONSANGUINEOUS MARRIAGES is considerable. The dominant pattern of deafness observed in this population was autosomal recessive.

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APA: Copy

FOROUGHMAND, ALI MOHAMMAD, GALEHDARI, HAMID, MOHAMMADIAN, GHOLAMREZA, RASEKH, ABDOLRAHMAN, & GHAVABESH, JASEM. (2011). THE FIRST SURVEY OF DISTRIBUTION OF INHERITED DEAFNESS PATTERNS IN INDIVIDUALS REFERRED TO GENETIC CENTER OF AHVAZ WELFARE ORGANIZATION, SOUTHERN IRAN. AUDITORY AND VESTIBULAR RESEARCH, 20(2 (36)), 73-78. SID. https://sid.ir/paper/400132/en

Vancouver: Copy

FOROUGHMAND ALI MOHAMMAD, GALEHDARI HAMID, MOHAMMADIAN GHOLAMREZA, RASEKH ABDOLRAHMAN, GHAVABESH JASEM. THE FIRST SURVEY OF DISTRIBUTION OF INHERITED DEAFNESS PATTERNS IN INDIVIDUALS REFERRED TO GENETIC CENTER OF AHVAZ WELFARE ORGANIZATION, SOUTHERN IRAN. AUDITORY AND VESTIBULAR RESEARCH[Internet]. 2011;20(2 (36)):73-78. Available from: https://sid.ir/paper/400132/en

IEEE: Copy

ALI MOHAMMAD FOROUGHMAND, HAMID GALEHDARI, GHOLAMREZA MOHAMMADIAN, ABDOLRAHMAN RASEKH, and JASEM GHAVABESH, “THE FIRST SURVEY OF DISTRIBUTION OF INHERITED DEAFNESS PATTERNS IN INDIVIDUALS REFERRED TO GENETIC CENTER OF AHVAZ WELFARE ORGANIZATION, SOUTHERN IRAN,” AUDITORY AND VESTIBULAR RESEARCH, vol. 20, no. 2 (36), pp. 73–78, 2011, [Online]. Available: https://sid.ir/paper/400132/en

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