DIFFERENTIATION OF HUMAN PLACENTA-DERIVED CHORIONIC STEM CELLS INTO OSTEOBLASTS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ALI AGHAEI SHAFIABADI A.; SEYED JAFARI S.S.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES Year:2009 | Volume:18 | Issue:71 Page(s): 1-6

Download Full-Text

Persian Verion

View:

1,224

Download:

Cites:

Information Journal Paper

Title

DIFFERENTIATION OF HUMAN PLACENTA-DERIVED CHORIONIC STEM CELLS INTO OSTEOBLASTS

Author(s)

ALI AGHAEI SHAFIABADI A. | SEYED JAFARI S.S. | Issue Writer Certificate

Keywords

CHORIONQ3

MESENCHYMAL STEM CELLSQ1

OSTEOBLASTQ3

Abstract

Introduction: MESENCHYMAL STEM CELLS (MSCs) from various sources are capable of differentiating into different cell lineages under proper culture condition. Recently, human placenta appeared on the stage in the search for MSCs. Human derived CHORIONic villi stem cells, are cells with high proliferation and multipotential and will be differentiate other cells.Objective: Differentiation of Human Placenta-derived CHORIONic Stem Cells into OSTEOBLASTs.Materials and Methods: CHORIONic derived Villi Stem Cells isolated from the human term placenta. Cells collected and cultured at DMEM/F12 medium. Osteogenic differentiation was induced with DMEM/F12 media (10%FBS) with 0.1mM dexamethasone and 50mM Ascorbic Acid 3-Phosphate. Mineralized matrix was evaluated by von kossa staining. Results: The CHORIONic stem cells when plated, exhibited a population of fibroblast–like cells morphologically. This cells in osteogenic media containing Dexamethasone and Ascorbat Phosphate exhibited morphologic changes in cell structure after 7 days in culture. Cells changed from an elongated fibroblastic appearance to a rounded more cuboidal shape. The cells cultured with osteogenic factors were stained positively for mineralized nodular structures, as confirmed by von kossa staining. Secretion of calcified extracellular matrix was observed as black nodules. Secretion of cacified extracellular matrix was not observed in control group containing only CHORIONic stem cells without osteogenic media.Conclusion: we have reported osteogenic differentiation with using placenta derived CHORIONic stem cells. The results of these in vitro studies suggested that placenta derived CHORIONic stem cells one of the possible allogeneic sources for tissue engineering in the bone diseases

Cites

No record.

References

No record.

Cite

APA: Copy

ALI AGHAEI SHAFIABADI, A., & SEYED JAFARI, S.S.. (2009). DIFFERENTIATION OF HUMAN PLACENTA-DERIVED CHORIONIC STEM CELLS INTO OSTEOBLASTS. JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, 18(71), 1-6. SID. https://sid.ir/paper/40072/en

Vancouver: Copy

ALI AGHAEI SHAFIABADI A., SEYED JAFARI S.S.. DIFFERENTIATION OF HUMAN PLACENTA-DERIVED CHORIONIC STEM CELLS INTO OSTEOBLASTS. JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;18(71):1-6. Available from: https://sid.ir/paper/40072/en

IEEE: Copy

A. ALI AGHAEI SHAFIABADI, and S.S. SEYED JAFARI, “DIFFERENTIATION OF HUMAN PLACENTA-DERIVED CHORIONIC STEM CELLS INTO OSTEOBLASTS,” JOURNAL OF GUILAN UNIVERSITY OF MEDICAL SCIENCES, vol. 18, no. 71, pp. 1–6, 2009, [Online]. Available: https://sid.ir/paper/40072/en

Related Journal Papers