EVALUATION OF EFFECTS OF DILUTED AMNIOTIC FLUID ON HISTOLOGICAL CHANGES OF INTESTINE OF RABBIT FETUS WITH GASTROSCHISIS

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ASHRAFI MAHMOUD; HOSSEINPOUR MEHRDAD; FARID M.; SANEEI M.H.; YOUNESI S.; YADEGARI M.; VAHED E.

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Journal: Iranian Journal of Surgery Year:2006 | Volume:14 | Issue:3 Page(s): 0-0

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Title

EVALUATION OF EFFECTS OF DILUTED AMNIOTIC FLUID ON HISTOLOGICAL CHANGES OF INTESTINE OF RABBIT FETUS WITH GASTROSCHISIS

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Keywords

GASTROSCHISISQ4

AMNIOTIC FLUIDQ4

FETUSQ4

RABBITQ3

Abstract

Introduction & Objective: Intestinal damage in GASTROSCHISIS is due to contact of intestinal wall with AMNIOTIC FLUID. In this study effects of fluid dilution on histological changes of intestine in RABBIT FETUS were evaluated.Materials & Methods: In an experimental clinical trial, 10 RABBIT FETUSes as shams 7 an FETUSes as controls and 7 FETUSes as cases were studied. In shams, after delivery abdomen of FETUS was opened and FETUS was placed in formalin. In controls, with fetal surgery, we produce GASTROSCHISIS. In cases, before closure of hystrotomy, a 14 central vein catheter was placed in uterus and 6 hours later, AMNIOTIC FLUID was diluted by injection of 1-2 cc of warm normal saline every four hours. Forty-eight hours later, FETUSes were delivered by Cesarean section and analyzed histologically.Results: There were no differences between, mucosa, submucosa, muscularis thickness and ganglion cell in groups. Serosal thickness was 4.5±3.6 mm in shams 64.2±28.7 mm in controls and 6±4.1 mm in cases group.In control group, serosal thickness was higher than shams (P=0.001) and case group (P=0.002). In histological evaluation, fibroblast infiltration and collagen deposition with fibrin were seen in serosal layer.Conclusions: With intermittently dilution of AMNIOTIC FLUID, we can prevent the effects of this fluid on in fetal intestine histology.

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APA: Copy

ASHRAFI, MAHMOUD, HOSSEINPOUR, MEHRDAD, FARID, M., SANEEI, M.H., YOUNESI, S., YADEGARI, M., & VAHED, E.. (2006). EVALUATION OF EFFECTS OF DILUTED AMNIOTIC FLUID ON HISTOLOGICAL CHANGES OF INTESTINE OF RABBIT FETUS WITH GASTROSCHISIS. IRANIAN JOURNAL OF SURGERY, 14(3), 0-0. SID. https://sid.ir/paper/400945/en

Vancouver: Copy

ASHRAFI MAHMOUD, HOSSEINPOUR MEHRDAD, FARID M., SANEEI M.H., YOUNESI S., YADEGARI M., VAHED E.. EVALUATION OF EFFECTS OF DILUTED AMNIOTIC FLUID ON HISTOLOGICAL CHANGES OF INTESTINE OF RABBIT FETUS WITH GASTROSCHISIS. IRANIAN JOURNAL OF SURGERY[Internet]. 2006;14(3):0-0. Available from: https://sid.ir/paper/400945/en

IEEE: Copy

MAHMOUD ASHRAFI, MEHRDAD HOSSEINPOUR, M. FARID, M.H. SANEEI, S. YOUNESI, M. YADEGARI, and E. VAHED, “EVALUATION OF EFFECTS OF DILUTED AMNIOTIC FLUID ON HISTOLOGICAL CHANGES OF INTESTINE OF RABBIT FETUS WITH GASTROSCHISIS,” IRANIAN JOURNAL OF SURGERY, vol. 14, no. 3, pp. 0–0, 2006, [Online]. Available: https://sid.ir/paper/400945/en

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