Assessment of the effect of smoking reduction on liver function tests and metabolic indices in non-alcoholic steatohepatitis smokers

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JAMALI R.; AGHAMOHAMMADI M.; Paknejad o.; Karbalai Saleh S.

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Journal: Feyz Medical Sciences Journal Year:2020 | Volume:24 | Issue:4 Page(s): 404-412

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Title

Assessment of the effect of smoking reduction on liver function tests and metabolic indices in non-alcoholic steatohepatitis smokers

Author(s)

JAMALI R. | AGHAMOHAMMADI M. | Paknejad o. | Karbalai Saleh S. | Issue Writer Certificate

Keywords

SmokingQ3

Liver function testsQ1

Metabolic indexesQ1

Non-alcoholic steatohepatitisQ1

Abstract

Background: This study aimed to investigate the effects of Smoking reduction on Liver function tests and metabolic parameters in Non-alcoholic steatohepatitis (NASH) smokers. Materials and Methods: In addition to standard treatment, all patients participated in 6 sessions of “ motivational interview” workshops to encourage Smoking decrement. The clinical trial consisted of two successful and unsuccessful arms. Those who decreased daily cigarette Smoking more than 50% were labeled as “ successful” group. The “ unsuccessful” group consisted of those who were decreased the daily cigarette Smoking less than 50%. The successful and unsuccessful groups were 43 (41%) and 61 (59%) patients respectively. The data regarding number of daily cigarette Smoking, Liver function tests and metabolic parameters were checked twice, in 3 and 6 months’ time after starting the intervention. Results: Liver function tests, metabolic parameters and liver fat content (LFC) were decreased in both arms after 6 months. The mean alanine aminotransferase, alkaline phosphatase, fasting blood sugar, insulin, cholesterol, low density lipoprotein, LFC, and waist circumference (WC) was lower in successful arm than in unsuccessful. Conclusion: It seems that concomitant standard treatment and cigarette Smoking reduction has more effect in decrement of alanine aminotransferase, serum metabolic parameters, WC and LFC in NASH smokers.

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APA: Copy

JAMALI, R., AGHAMOHAMMADI, M., Paknejad, o., & Karbalai Saleh, S.. (2020). Assessment of the effect of smoking reduction on liver function tests and metabolic indices in non-alcoholic steatohepatitis smokers. FEYZ, 24(4 ), 404-412. SID. https://sid.ir/paper/401728/en

Vancouver: Copy

JAMALI R., AGHAMOHAMMADI M., Paknejad o., Karbalai Saleh S.. Assessment of the effect of smoking reduction on liver function tests and metabolic indices in non-alcoholic steatohepatitis smokers. FEYZ[Internet]. 2020;24(4 ):404-412. Available from: https://sid.ir/paper/401728/en

IEEE: Copy

R. JAMALI, M. AGHAMOHAMMADI, o. Paknejad, and S. Karbalai Saleh, “Assessment of the effect of smoking reduction on liver function tests and metabolic indices in non-alcoholic steatohepatitis smokers,” FEYZ, vol. 24, no. 4 , pp. 404–412, 2020, [Online]. Available: https://sid.ir/paper/401728/en

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