SURVEY ON THE PROTECTIVE EFFECT OF TOTAL HYDRO-ALCOHOLIC EXTRACT OF ARTEMISIA AUCHERI ON MERCURIC CHLORIDE-INDUCED NEPHROTOXICITY IN MALE MICE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HAKIMIZADEH ELHAM; BANIASADI POUR HANIEH; REZAZADEH HOSSEIN; ANSARI JABERI ALI; MASHAYEKHI NARGES; ISMAILI MARZIEH; NEJAD HASSAN REZA; AMIN FATEMEH; SHAMSIZADEH ALI; AYOOBI FATEMEH; ZARE LIDA; ALLAHTAVAKOLI MOHAMMAD

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Forensic Medicine Year:2013 | Volume:19 | Issue:2-3 (68) Page(s): 251-256

Download Full-Text

Persian Verion

View:

793

Download:

Cites:

Information Journal Paper

Title

SURVEY ON THE PROTECTIVE EFFECT OF TOTAL HYDRO-ALCOHOLIC EXTRACT OF ARTEMISIA AUCHERI ON MERCURIC CHLORIDE-INDUCED NEPHROTOXICITY IN MALE MICE

Author(s)

Keywords

ARTEMISIAQ2

NEPHROTOXICITYQ2

MERCURY CHLORIDEQ2

Abstract

Background: Heavy metals cause to NEPHROTOXICITY in kidney tissue of human and animals through increased production of oxygen free radicals. Plants Antioxidants are of good choices for protection against the toxicity of these compounds. In the current study, the protective effect of hydro alcoholic extract of ARTEMISIA was assessed on Mercuric chloride-induced NEPHROTOXICITY.Methods: In this study 28 male mice were used. Animals were randomly divided into 4 groups (N=7) as: 1 -Control, 2 - Mercuric chloride, 3 - Mercuric chloride with extract of ARTEMISIA and 4 – Extract of ARTEMISIA groups. Mercuric chloride and ARTEMISIA extracts intra-peritoneal were injected with the dose of 1.5 mg/kg and 200 mg/kg for 8 days, respectively. Then, blood samples were prepared and NEPHROTOXICITY was determined by measuring serum urea and creatinine, using spectrophotometry (device SINCO) and specific kit (Pars test). Data were reported as Mean±SEM via SPSS software. One-way ANOVA followed by Tukey test was used for data analysis and P<0.05 was considered as a significant difference.Findings: Compared to the Mercuric chloride group, ARTEMISIA extract caused a significant decrease in serum urea and creatinine in the combined ARTEMISIA extract with Mercuric chloride group. Mercuric chloride also caused a significant increase in serum urea and creatinine in the Mercuric chloride group compared to the control group.Conclusion: Our results showed that the extract of ARTEMISIA has protective effects against NEPHROTOXICITY induced by heavy metals such as mercury.

Cites

No record.

References

No record.

Cite

APA: Copy

HAKIMIZADEH, ELHAM, BANIASADI POUR, HANIEH, REZAZADEH, HOSSEIN, ANSARI JABERI, ALI, MASHAYEKHI, NARGES, ISMAILI, MARZIEH, NEJAD HASSAN, REZA, AMIN, FATEMEH, SHAMSIZADEH, ALI, AYOOBI, FATEMEH, ZARE, LIDA, & ALLAHTAVAKOLI, MOHAMMAD. (2013). SURVEY ON THE PROTECTIVE EFFECT OF TOTAL HYDRO-ALCOHOLIC EXTRACT OF ARTEMISIA AUCHERI ON MERCURIC CHLORIDE-INDUCED NEPHROTOXICITY IN MALE MICE. SCIENTIFIC JOURNAL OF FORENSIC MEDICINE, 19(2-3 (68)), 251-256. SID. https://sid.ir/paper/404003/en

Vancouver: Copy

HAKIMIZADEH ELHAM, BANIASADI POUR HANIEH, REZAZADEH HOSSEIN, ANSARI JABERI ALI, MASHAYEKHI NARGES, ISMAILI MARZIEH, NEJAD HASSAN REZA, AMIN FATEMEH, SHAMSIZADEH ALI, AYOOBI FATEMEH, ZARE LIDA, ALLAHTAVAKOLI MOHAMMAD. SURVEY ON THE PROTECTIVE EFFECT OF TOTAL HYDRO-ALCOHOLIC EXTRACT OF ARTEMISIA AUCHERI ON MERCURIC CHLORIDE-INDUCED NEPHROTOXICITY IN MALE MICE. SCIENTIFIC JOURNAL OF FORENSIC MEDICINE[Internet]. 2013;19(2-3 (68)):251-256. Available from: https://sid.ir/paper/404003/en

IEEE: Copy

ELHAM HAKIMIZADEH, HANIEH BANIASADI POUR, HOSSEIN REZAZADEH, ALI ANSARI JABERI, NARGES MASHAYEKHI, MARZIEH ISMAILI, REZA NEJAD HASSAN, FATEMEH AMIN, ALI SHAMSIZADEH, FATEMEH AYOOBI, LIDA ZARE, and MOHAMMAD ALLAHTAVAKOLI, “SURVEY ON THE PROTECTIVE EFFECT OF TOTAL HYDRO-ALCOHOLIC EXTRACT OF ARTEMISIA AUCHERI ON MERCURIC CHLORIDE-INDUCED NEPHROTOXICITY IN MALE MICE,” SCIENTIFIC JOURNAL OF FORENSIC MEDICINE, vol. 19, no. 2-3 (68), pp. 251–256, 2013, [Online]. Available: https://sid.ir/paper/404003/en

Related Journal Papers