Plasma levels of omentin in patients with medullary thyroid carcinoma

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Norasti Fatemeh; ZARIF YEGANEH MARJAN; SHEIKHOLESLAMI SARA; HOGHOOGHI RAD LALEH; GOLAB GHADAKSAZ HODA; HEDAYATI MEHDI

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Journal: Koomesh Year:2019 | Volume:21 | Issue:1 (73) Page(s): 83-86

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Title

Plasma levels of omentin in patients with medullary thyroid carcinoma

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Keywords

Thyroid NeoplasmsQ2

AdipokineQ1

OmentinQ1

Abstract

Introduction: Medullary thyroid carcinoma (MTC) accounts for 5-10% of thyroid malignancies. The origin of medullary thyroid cancer is para-follicular cells of the thyroid. Several studies showed that relationship between Adipokines and cancers. Omentin is an Adipokine secreted from adipose tissue. The aim of this study was to investigate the relationship between plasma levels of Omentin in patients with medullary thyroid cancer. Materials and Methods: In this case-control study, 90 individuals were studied (45 cases and 45 controls). Omentin plasma levels of these individuals were measured by ELISA method. Results: In general, plasma levels of omnentin in all patients with MTC was significantly higher than the control group (P = 0. 002). Omentin plasma levels in both women and men with MTC were ignificantly higher than the corresponding control group (P = 0. 0371, and P = 0. 0240, respectively). Conclusion: The results of this study showed that plasma levels Omentin in patients with MTV were higher than the healthy group. Thus Omentin may be considered as a novel and promising biomarker for diagnosis or confirmation of MTC.

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APA: Copy

Norasti, Fatemeh, ZARIF YEGANEH, MARJAN, SHEIKHOLESLAMI, SARA, HOGHOOGHI RAD, LALEH, GOLAB GHADAKSAZ, HODA, & HEDAYATI, MEHDI. (2019). Plasma levels of omentin in patients with medullary thyroid carcinoma. KOOMESH, 21(1 (73) ), 83-86. SID. https://sid.ir/paper/405262/en

Vancouver: Copy

Norasti Fatemeh, ZARIF YEGANEH MARJAN, SHEIKHOLESLAMI SARA, HOGHOOGHI RAD LALEH, GOLAB GHADAKSAZ HODA, HEDAYATI MEHDI. Plasma levels of omentin in patients with medullary thyroid carcinoma. KOOMESH[Internet]. 2019;21(1 (73) ):83-86. Available from: https://sid.ir/paper/405262/en

IEEE: Copy

Fatemeh Norasti, MARJAN ZARIF YEGANEH, SARA SHEIKHOLESLAMI, LALEH HOGHOOGHI RAD, HODA GOLAB GHADAKSAZ, and MEHDI HEDAYATI, “Plasma levels of omentin in patients with medullary thyroid carcinoma,” KOOMESH, vol. 21, no. 1 (73) , pp. 83–86, 2019, [Online]. Available: https://sid.ir/paper/405262/en

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