EFFECT OF PAMIDRONATE ON TOOTH MOVEMENT AND ROOT RESORPTION IN RAT

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SEYFI MASOUD; AGHAEIPOUR N.

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Paper Information

Journal: Journal of Dental School Year:2009 | Volume:27 | Issue:2 (80) Page(s): 67-71

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Information Journal Paper

Title

EFFECT OF PAMIDRONATE ON TOOTH MOVEMENT AND ROOT RESORPTION IN RAT

Author(s)

SEYFI MASOUD | AGHAEIPOUR N. | Issue Writer Certificate

Keywords

PAMIDRONATEQ3

ROOT RESORPTIONQ3

ORTHODONTIC TOOTH MOVEMENTQ3

Abstract

Background and Aim: The purpose of this study is to examine the effect of administration of bisphosphonate; an antiosteoclastic agent i.e. PAMIDRONATE, on the ORTHODONTIC TOOTH MOVEMENT and ROOT RESORPTION in rats.Materials & Methods: The present experimental study was conducted on 30 male 8 weeks old Wistar rat. On day zero the orthodontic appliance was installed. Control group received normal saline and for experimental groups, PAMIDRONATE 1mg/kg, was injected intraperitoneally. After 21 days, rats of control group and experimental were sacrificed and the upper jaws were dissected and the distance between upper 1st and 2nd molars were measured. Under light microscope root resorptive lacunae were calculated by computer software. Student t-test was used for purpose of comparison between groups.Results: There were significant differences between the control (0.562±0.168 mm) and the experimental group (0.346±0.197 mm) for ORTHODONTIC TOOTH MOVEMENTs (p<0.01 by paired t-test). Looking to ROOT RESORPTION no significant differences were observed between the control (0.25± 0.175×10-2 square millimeter) and the experimental group (0.26±0.125×10-2 square millimeter).Conclusion: According to the present study, PAMIDRONATE can reduce tooth movement and at the same time no increase of the ROOT RESORPTION is observed.

Cites

THE EFFECT OF AN ANGIOGENIC CYTOKINE ON ORTHODONTICALLY INDUCED INFLAMMATORY ROOT RESORPTION

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APA: Copy

SEYFI, MASOUD, & AGHAEIPOUR, N.. (2009). EFFECT OF PAMIDRONATE ON TOOTH MOVEMENT AND ROOT RESORPTION IN RAT. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, 27(2 (80)), 67-71. SID. https://sid.ir/paper/405837/en

Vancouver: Copy

SEYFI MASOUD, AGHAEIPOUR N.. EFFECT OF PAMIDRONATE ON TOOTH MOVEMENT AND ROOT RESORPTION IN RAT. JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE[Internet]. 2009;27(2 (80)):67-71. Available from: https://sid.ir/paper/405837/en

IEEE: Copy

MASOUD SEYFI, and N. AGHAEIPOUR, “EFFECT OF PAMIDRONATE ON TOOTH MOVEMENT AND ROOT RESORPTION IN RAT,” JOURNAL OF DENTAL SCHOOL SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCE, vol. 27, no. 2 (80), pp. 67–71, 2009, [Online]. Available: https://sid.ir/paper/405837/en

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