EVALUATION OF ANTIOXIDANT PROPERTIES IN 28 HERBS IN IRAN

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ZARBAN A.; MALKANEH M.; HASANPOUR M.; NAJARI M.T.; ABAD M.

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Journal: Journal of Birjand University of Medical Sciences Year:2004 | Volume:11 | Issue:1 Page(s): 5-12

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Title

EVALUATION OF ANTIOXIDANT PROPERTIES IN 28 HERBS IN IRAN

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Keywords

HERBAL MEDICINEQ2

ANTIOXIDANTSQ4

OXIDATIVE STRESSQ2

FRAPQ2

RED BLOOD CELL HEMOLYSISQ4

Abstract

Background and Aim: The subject of free radicals and reactive oxygen species and their effects on the biological systems is one of the important subjects in medicine. These agents can irreversibly damage to the vital molecules such as nucleic acids, proteins, lipids and lipoproteins. ANTIOXIDANTS can protect biological systems against these agents. Consuming of some herbs that have high amounts of antioxidant can be useful in human health. The aim of this study is the investigation of antioxidant properties in some herbs in IRAN. Materials and Methods: on the basis of existing information in traditional medicine, twenty-eight herbs that were effective in lowering blood sugar, blood lipids, hypertension and arteriosclerosis were prepared. After that we determined the total antioxidant power by FRAP (Ferric Reducing / Antioxidant Power) method. Also we evaluate the ability of the extracts with different concentrations in inhibition of red blood cell (RBC) hemolysis induced by hydrogen peroxide (H2O2). The results were calculated and compared by mean and standard deviation obtained from experiments that were carried out minimum three times. The statistical test of the one sample t. test was used for comparison of different concentrations.Results: In among of the plants aqueous extracts the most antioxidant power was observed in Origanum Vulgare L., Rosa Damascena Mill, Salvia Officinalis L., Viscum Album L., Melitous Officianalis, lea of Juglans Regia L. and Crataegus Spp. Also there was a positive and significant correlation between antioxidant power of aqueous and alcoholic extracts (r=0.671, P<0.001). The plants with high antioxidant capacity showed more ability on the inhibition of RBC hemolysis induced by H2O2 (P<0.05) and with the increase of antioxidant power the inhibition rate of RBC hemolysis increased (r=0.646, P<0.007). Although some of the herbs had peroxidant properties and caused the increase of RBC hemolysis.Conclusion: Since some of the traditional HERBAL MEDICINE have high amounts of natural antioxidant and can naturalize the activity of free radicals, it is suggested that these herbs use for preventing of different diseases and also for helping to the treatment of some diseases in beside of new chemical drugs.

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APA: Copy

ZARBAN, A., MALKANEH, M., HASANPOUR, M., NAJARI, M.T., & ABAD, M.. (2004). EVALUATION OF ANTIOXIDANT PROPERTIES IN 28 HERBS IN IRAN . JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 11(1), 5-12. SID. https://sid.ir/paper/406398/en

Vancouver: Copy

ZARBAN A., MALKANEH M., HASANPOUR M., NAJARI M.T., ABAD M.. EVALUATION OF ANTIOXIDANT PROPERTIES IN 28 HERBS IN IRAN . JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2004;11(1):5-12. Available from: https://sid.ir/paper/406398/en

IEEE: Copy

A. ZARBAN, M. MALKANEH, M. HASANPOUR, M.T. NAJARI, and M. ABAD, “EVALUATION OF ANTIOXIDANT PROPERTIES IN 28 HERBS IN IRAN ,” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 11, no. 1, pp. 5–12, 2004, [Online]. Available: https://sid.ir/paper/406398/en

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