Effect of resistance training and Resveratrol supplementation on muscle regeneration of MyoD and eMHC in CT-26 colon cancer mice

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Asadmanesh Enayatollah; Koushkie Jahromi Maryam; SAMADI MAHDI; DARYANOOSH FARHAD; Neamati Javad

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES Year:2020 | Volume:22 | Issue:2 (74) Page(s): 40-48

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

394

Download:

Cites:

Information Journal Paper

Title

Effect of resistance training and Resveratrol supplementation on muscle regeneration of MyoD and eMHC in CT-26 colon cancer mice

Author(s)

Keywords

Resistance TrainingQ1

ResveratrolQ1

MyoD ProteinQ1

CancerQ2

Abstract

Background and Objective: Physical exercise and nutrition supplements are recommended interventions to reduce cachexia. This study was conducted to determine the effect of Resistance Training and Resveratrol supplementation on muscle regeneration indices of MyoD (myoblast determination protein) and eMHC (embryonic Myosin Heavy Chain) in CT-26 colon Cancer mice. Methods: This experimental study was performed on 20 six-week-old BALB/c mice to which CT-26 tumor was implanted. The mice were divided into four groups of Resistance Training, Resveratrol, combination of Resveratrol with Resistance Training, and control. The Resistance Training group performed six weeks of progressive Resistance Training. The Resveratrol group received 100 mg/kg Resveratrol per day, and the control and Resistance Training group received the solution of Methyl cellulose through gavage. In gastrocnemius muscle MyoD Protein and eMHC level were measured using western blot and ELISA methods, respectively. Results: eMHC protein in combination of Resveratrol with exercise group (4. 66± 0. 25) increased significantly compared to the exercise group (3. 46± 0. 64) (P<0. 05). Body weight of mice without tumor (21. 50± 1. 30) in the Resistance Training group increased significantly compared to other groups (P<0. 05). There was no significant difference in the tumor weight of mice and MyoD Protein in expermental groups. Conclusion: Regarding the increasing effect of combination of Resveratrol with exercise group compared to Resistance Training group on eMHC, Resveratrol supplementation at higher doses may be recommended along with Resistance Training to improve muscle regeneration.

Cites

No record.

References

Cite

APA: Copy

Asadmanesh, Enayatollah, Koushkie Jahromi, Maryam, SAMADI, MAHDI, DARYANOOSH, FARHAD, & Neamati, Javad. (2020). Effect of resistance training and Resveratrol supplementation on muscle regeneration of MyoD and eMHC in CT-26 colon cancer mice. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, 22(2 (74) ), 40-48. SID. https://sid.ir/paper/406703/en

Vancouver: Copy

Asadmanesh Enayatollah, Koushkie Jahromi Maryam, SAMADI MAHDI, DARYANOOSH FARHAD, Neamati Javad. Effect of resistance training and Resveratrol supplementation on muscle regeneration of MyoD and eMHC in CT-26 colon cancer mice. JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;22(2 (74) ):40-48. Available from: https://sid.ir/paper/406703/en

IEEE: Copy

Enayatollah Asadmanesh, Maryam Koushkie Jahromi, MAHDI SAMADI, FARHAD DARYANOOSH, and Javad Neamati, “Effect of resistance training and Resveratrol supplementation on muscle regeneration of MyoD and eMHC in CT-26 colon cancer mice,” JOURNAL OF GORGAN UNIVERSITY OF MEDICAL SCIENCES, vol. 22, no. 2 (74) , pp. 40–48, 2020, [Online]. Available: https://sid.ir/paper/406703/en

Related Journal Papers