A STUDY OF ANALGESIC EFFECT OF AQUEOUS EXTRACT OF MENTHE SPICATA IN RATS

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NOUR ALDINI M.; NOUREDDIN M.; SALAMI M.; MESDAGHINIA A.R.; VERDI J.; SALIMIAN M.

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Journal: Feyz Medical Sciences Journal Year:2007 | Volume:10 | Issue:4 (SERIAL 40) Page(s): 19-23

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Title

A STUDY OF ANALGESIC EFFECT OF AQUEOUS EXTRACT OF MENTHE SPICATA IN RATS

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Keywords

MEDICAL PLANTQ4

SPEARMINTQ2

PAIN MEASUREMENTQ4

Abstract

Background: In this study, the analgesic effect of aqueous extract of SPEARMINT, which has been used in traditional as an anaigesic anti-rheumatic, medicine was considered.Materials and Methods: 90 male rats, weighing 200-250g, were in 10 groups. Aqueous extract of SPEARMINT with different doses including. 0.9, 2.7, 6, 35 and 45 mg/Kg was injected divided to the experimental animals the positive control group received Aspirin with diffe the positive control group rent doses of 50, 100, and 300 mg/Kg Normal saline (1ml/K.g) was injected to the negative group. Hotplate method was used for evaluating the analgesic effect of the SPEARMINT extracts and the drug were measured in periods of 15, 30, 45 and 60 minutes after injection. Results: The results showed that the extract at a doses of 2.7 and6 mg/Kg has a significant analgesic effect with the highest analgesic effect by the letter. In addition, the results indicated that the 6 mg/Kg of menthe spicata extract was more effective than aspirin 300 mg/Kg in the posi tire group.Conclusion: It seems that dose of the aqueous extract of SPEARMINT has morked analgesic effect and can be considered as a herbal medicine in pain treatment in Hume decrease in neuron permeability of Ca++.

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APA: Copy

NOUR ALDINI, M., NOUREDDIN, M., SALAMI, M., MESDAGHINIA, A.R., VERDI, J., & SALIMIAN, M.. (2007). A STUDY OF ANALGESIC EFFECT OF AQUEOUS EXTRACT OF MENTHE SPICATA IN RATS. FEYZ, 10(4 (SERIAL 40)), 19-23. SID. https://sid.ir/paper/40810/en

Vancouver: Copy

NOUR ALDINI M., NOUREDDIN M., SALAMI M., MESDAGHINIA A.R., VERDI J., SALIMIAN M.. A STUDY OF ANALGESIC EFFECT OF AQUEOUS EXTRACT OF MENTHE SPICATA IN RATS. FEYZ[Internet]. 2007;10(4 (SERIAL 40)):19-23. Available from: https://sid.ir/paper/40810/en

IEEE: Copy

M. NOUR ALDINI, M. NOUREDDIN, M. SALAMI, A.R. MESDAGHINIA, J. VERDI, and M. SALIMIAN, “A STUDY OF ANALGESIC EFFECT OF AQUEOUS EXTRACT OF MENTHE SPICATA IN RATS,” FEYZ, vol. 10, no. 4 (SERIAL 40), pp. 19–23, 2007, [Online]. Available: https://sid.ir/paper/40810/en

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