THE IMPACT OF VITAMIN C AND E, MAGNESIUM AND ZINC ON GLYCEMIC CONTROL AND INSULIN RESISTANCE IN TYPE II DIABETIC PATIENTS

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FARVID M.A.S.; SIASI F.; JALAI M.

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Journal: TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ) Year:2007 | Volume:64 | Issue:10 Page(s): 77-85

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Title

THE IMPACT OF VITAMIN C AND E, MAGNESIUM AND ZINC ON GLYCEMIC CONTROL AND INSULIN RESISTANCE IN TYPE II DIABETIC PATIENTS

Author(s)

FARVID M.A.S. | SIASI F. | JALAI M. | Issue Writer Certificate

Keywords

VITAMIN CQ3

VITAMIN EQ3

MAGNESIUMQ3

ZINCQ3

MICOALBUMINURIAQ3

GLYCEMIC CONTROLQ3

INSULIN RESISTANCEQ2

Abstract

Background: The present study designed to assess the effect of Mg+Zn, VITAMIN C+E, and combination of these micronutrients on GLYCEMIC CONTROL and INSULIN RESISTANCE in type 2 diabetic patients.Methods: In a randomized, double-blind, placebo controlled clinical trial, 69 type 2 diabetic patients were randomly divided into four groups, each group receiving one of the following daily supplement for 3 months; group M: 200 mg and 30 mg Zn (n=16), group V: 200 mg VITAMIN C and 150 mg VITAMIN E (n=18), group MV: minerals plus vitamins (n=17), group P: placebo (n=18).Fasting blood glucose, fructosamine, HbA1c and serum insulin were measured at the beginning and at the end of 3 months supplementation. INSULIN RESISTANCE was calculated by HOMA score. Treatment effects were analyzed by general linear modeling.Results: After 3 months of supplementation fasting blood glucose decreased in MV group (165±46 vs 177±41 mg/dl, p=0.035). There was no significant change in fructoseamin, HbA1c, serum insulin or INSULIN RESISTANCE in treatment groups.Conclusion: The results of the present study provide evidence for the effects of combination of Mg, Zn and VITAMIN C and E supplementations on improvement of fasting blood glucose but not fructosamine, HbA1c, serum insulin or INSULIN RESISTANCE in type 2 diabetic patients.

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References

IMPACT OF VITAMIN AND/OR MINERAL SUPPLEMENTATION ON LIPID PROFILES IN TYPE 2 DIABETES

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APA: Copy

FARVID, M.A.S., SIASI, F., & JALAI, M.. (2007). THE IMPACT OF VITAMIN C AND E, MAGNESIUM AND ZINC ON GLYCEMIC CONTROL AND INSULIN RESISTANCE IN TYPE II DIABETIC PATIENTS. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), 64(10), 77-85. SID. https://sid.ir/paper/408340/en

Vancouver: Copy

FARVID M.A.S., SIASI F., JALAI M.. THE IMPACT OF VITAMIN C AND E, MAGNESIUM AND ZINC ON GLYCEMIC CONTROL AND INSULIN RESISTANCE IN TYPE II DIABETIC PATIENTS. TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ)[Internet]. 2007;64(10):77-85. Available from: https://sid.ir/paper/408340/en

IEEE: Copy

M.A.S. FARVID, F. SIASI, and M. JALAI, “THE IMPACT OF VITAMIN C AND E, MAGNESIUM AND ZINC ON GLYCEMIC CONTROL AND INSULIN RESISTANCE IN TYPE II DIABETIC PATIENTS,” TEHRAN UNIVERSITY MEDICAL JOURNAL (TUMJ), vol. 64, no. 10, pp. 77–85, 2007, [Online]. Available: https://sid.ir/paper/408340/en

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