IMPACT OF VITAMIN AND/OR MINERAL SUPPLEMENTATION ON LIPID PROFILES IN TYPE 2 DIABETES

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FARVID M.A.S.; SIASI F.; JALALI M.; HOSSEINI M.; SAADAT N.

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Journal: IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM) Year:2004 | Volume:6 | Issue:2 (SN 22) Page(s): 115-122

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Title

IMPACT OF VITAMIN AND/OR MINERAL SUPPLEMENTATION ON LIPID PROFILES IN TYPE 2 DIABETES

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Keywords

TYPE 2 DIABETESQ2

VITAMIN CQ3

VITAMIN EQ2

MAGNESIUMQ3

ZINCQ3

LIPIDQ3

HDL-CQ4

APOLIPOPROTEINSQ4

Abstract

Introduction: The purpose of the present study was to assess the impact of Mg+Zn, VITAMIN C+E, and combination of these micronutrients on serum LIPID and lipoprotein profiles in type 2 diabetic patients. Material and Methods: In a randomized, double blind, placebo controlled clinical trial, 69 type 2 diabetic patients under diet and hypoglycemic drugs were randomly divided into four groups. Each group received one of the following daily supplement for 3 months; group M: 200 mg Mg and 30 mg Zn (n=16), group V: 200 mg VITAMIN C and 150 mg VITAMIN E (n=18), group MV: minerals plus vitamins (n=17), group P: placebo (n=18). Results: Results indicate that after 3 months of supplementation mean serum levels of HDL-C and apolipoprotein A1 increased significantly in the MV group by 24% (50.4±19.3vs. 40.6±10.8 mg/dL) and 9% (170±34 vs. 156±24 mg/dL), respectively (p<0.01). There were no significant changes in the levels of these parameters in the other 3 groups. Serum levels of total cholesterol, LDL-c, triglyceride, and apolipoprotein B were not altered after supplementation in all 4 groups. Conclusion: It is concluded that since co-supplementation of Mg, Zn, VITAMIN C and E significantly increases HDL-C and apolipoprotein A1, supplementation of these micronutrients should be recommended for type 2 diabetic patients based on their daily requirements.

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APA: Copy

FARVID, M.A.S., SIASI, F., JALALI, M., HOSSEINI, M., & SAADAT, N.. (2004). IMPACT OF VITAMIN AND/OR MINERAL SUPPLEMENTATION ON LIPID PROFILES IN TYPE 2 DIABETES. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 6(2 (SN 22)), 115-122. SID. https://sid.ir/paper/27227/en

Vancouver: Copy

FARVID M.A.S., SIASI F., JALALI M., HOSSEINI M., SAADAT N.. IMPACT OF VITAMIN AND/OR MINERAL SUPPLEMENTATION ON LIPID PROFILES IN TYPE 2 DIABETES. IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2004;6(2 (SN 22)):115-122. Available from: https://sid.ir/paper/27227/en

IEEE: Copy

M.A.S. FARVID, F. SIASI, M. JALALI, M. HOSSEINI, and N. SAADAT, “IMPACT OF VITAMIN AND/OR MINERAL SUPPLEMENTATION ON LIPID PROFILES IN TYPE 2 DIABETES,” IRANIAN JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 6, no. 2 (SN 22), pp. 115–122, 2004, [Online]. Available: https://sid.ir/paper/27227/en

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