Effects of combined therapy with resveratrol, continuous and interval exercises on apoptosis and lipid profiles in the liver of rats with nonalcoholic fatty liver disease

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Haj Ghasem Amir; FARZANEGI PARVIN; MAZAHERI ZOHREH

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Koomesh Year:2019 | Volume:21 | Issue:3 (75) Page(s): 540-548

Download Full-Text

Persian Verion

View:

330

Download:

Cites:

Information Journal Paper

Title

Effects of combined therapy with resveratrol, continuous and interval exercises on apoptosis and lipid profiles in the liver of rats with nonalcoholic fatty liver disease

Author(s)

Haj Ghasem Amir | FARZANEGI PARVIN | MAZAHERI ZOHREH | Issue Writer Certificate

Keywords

ApoptosisQ3

Oxidative StressQ2

Non-alcoholic Fatty LiverQ1

LipidQ3

ExerciseQ2

ResveratrolQ1

Abstract

Introduction: Non-alcoholic Fatty Liver disease (NAFLD) is one of the most common chronic liver disorders. In this study, effect of Resveratrol supplementation alone or in combination with interval and continuous Exercises was considered on hepatic cells Apoptosis and serum Lipid profiles in rats with NAFLD. Materials and Methods: Old rats were divided into two groups, including control and NAFLD. The NAFLD rats were then randomly divided into seven experimental sub-groups including NAFLD, NAFLSD + saline, NAFLD + Resveratrol (RSV), NAFLD + continuous Exercise, NAFLD + interval Exercise, NAFLD + continuous Exercise + RSV, and NAFLD + interval Exercise + RSV. Apoptosis biomarkers, including liver Bax and Bcl2 proteins, and serum Lipid profiles including HDL, LDL, total cholesterol (Cho) and triglyceride (TG), were measured using specific ELISA kits. Results: Resveratrol supplementation alone or in combination with Exercise training significantly decreased the serum LDL, Cho and TG levels (p<0. 05), but significantly increased the HDL level (p<0. 05). RSV alone or in combination with interval and continuous Exercise programs significantly decreased Bax protein content (p<0. 001), but significantly increased the Bcl2 level (p<0. 001). Conclusion: NAFLD is powerfully associated with the liver cells Apoptosis and abnormality in Lipid profiles. Although, Resveratrol supplementation alone has an anti-apoptotic and reducing effect on Lipid profiles, the combined therapy with Exercise training can be more effective.

Cites

No record.

References

No record.

Cite

APA: Copy

Haj Ghasem, Amir, FARZANEGI, PARVIN, & MAZAHERI, ZOHREH. (2019). Effects of combined therapy with resveratrol, continuous and interval exercises on apoptosis and lipid profiles in the liver of rats with nonalcoholic fatty liver disease. KOOMESH, 21(3 (75) ), 540-548. SID. https://sid.ir/paper/409101/en

Vancouver: Copy

Haj Ghasem Amir, FARZANEGI PARVIN, MAZAHERI ZOHREH. Effects of combined therapy with resveratrol, continuous and interval exercises on apoptosis and lipid profiles in the liver of rats with nonalcoholic fatty liver disease. KOOMESH[Internet]. 2019;21(3 (75) ):540-548. Available from: https://sid.ir/paper/409101/en

IEEE: Copy

Amir Haj Ghasem, PARVIN FARZANEGI, and ZOHREH MAZAHERI, “Effects of combined therapy with resveratrol, continuous and interval exercises on apoptosis and lipid profiles in the liver of rats with nonalcoholic fatty liver disease,” KOOMESH, vol. 21, no. 3 (75) , pp. 540–548, 2019, [Online]. Available: https://sid.ir/paper/409101/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops