COMPARISON OF PREGNANCY COMPLICATIONS BETWEEN GROUPS WITH DIET AND INSULIN THERAPY IN WOMEN WITH GESTATIONAL DIABETES MELLITUS

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KESHAVARZ M.; BABAEI GH.R.; AJAMI M.E.; DELVARIANZADEH M.

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Journal: Journal of Medical Council of Iran Year:2006 | Volume:23 | Issue:4 Page(s): 355-361

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Title

COMPARISON OF PREGNANCY COMPLICATIONS BETWEEN GROUPS WITH DIET AND INSULIN THERAPY IN WOMEN WITH GESTATIONAL DIABETES MELLITUS

Author(s)

KESHAVARZ M. | BABAEI GH.R. | AJAMI M.E. | DELVARIANZADEH M.

Keywords

GESTATIONAL DIABETESQ3

DIET AND INSULIN THERAPYQ3

PREGNANCY COMPLICATIONSQ4

Abstract

There are little data regarding the frequency of maternal, fetal and neonatal complications related to GESTATIONAL DIABETES mellitus (GDM) in Asian countries. Complications are thought to be higher than western countries, because of the poorer medical and obstetric facilities and lack of awareness. In an universal screening From 1310 pregnant women who were referred from private clinics and 8 health care centers to Fatemiyeh clinic, 63 women had GDM. All GDM women were controlled by researcher in Fatemiyeh clinic, also they were referred to the Sadri clinic (a specialized clinic) which was attended by a specialist team comprising obstetricians, an internal medicine physician, a dietitian and a nurse. Fasting and 2h post-prandial glucose values were evaluated weekly by formal laboratory method. All measurements of serum glucose were performed by the glucose oxidase method at the Fatemiyeh Hospital Laboratory. If the glucose level was not controlled the woman would be hospitalized and insulin prescribed by a physician.Of the 63 pregnant women with GDM, 50 (79%) were treated by diet alone and 13 (21%) had diet and insulin. Women with Insulin therapy were significantly older, obese and more parous. Delivery was earlier and had high blood glucose level during their pregnancy. The rate of glycosuria, age>30yr, obesity (BMI≥30Kg/m2), previous macrosomia, also elevated fasting blood glucose (FBG) in glucose tolerance test (GTT), GDM diagnosed before 12 weeks gestation, the rate of hydramnious (P<0.001, 33.3%), stillbirth (P<0.001, 33.3%), pre-eclampsia (P<0.05, 25%) and neonatal hypoglycemia (P<0.001, 58.3%) in women with insulin therapy had meaningful statistical differences with diet therapy group. Patients with GDM were scheduled for a 2-hour 75-gr oral glucose tolerance test at least 6-8 wks after delivery. All 8 women with overt diabetes were treated by insulin during pregnancy.The high level of PREGNANCY COMPLICATIONS in the group with insulin therapy was due to the high level of blood glucose during pregnancy thus awareness among these patients, strict dietary control.regulation in insulin injection, also use of glycometer set in order to daily control blood glucose is emphasized. Furthermore, the risk factors of glycosuria, age>30, obesity and previous macrosomia also GDM diagnosed in early pregnancy and elevated FBG in GTT must be noticed as predictor factors for the need for insulin therapy during pregnancy in GDM women.

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References

COMPARISON OF PREGNANCY COMPLICATIONS BETWEEN GESTATIONAL DIABETES MELLITUS AND NORMAL GROUP IN IRAN: A COHORT STUDY

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APA: Copy

KESHAVARZ, M., BABAEI, GH.R., AJAMI, M.E., & DELVARIANZADEH, M.. (2006). COMPARISON OF PREGNANCY COMPLICATIONS BETWEEN GROUPS WITH DIET AND INSULIN THERAPY IN WOMEN WITH GESTATIONAL DIABETES MELLITUS. JOURNAL OF MEDICAL COUNCIL OF I.R.I., 23(4), 355-361. SID. https://sid.ir/paper/41005/en

Vancouver: Copy

KESHAVARZ M., BABAEI GH.R., AJAMI M.E., DELVARIANZADEH M.. COMPARISON OF PREGNANCY COMPLICATIONS BETWEEN GROUPS WITH DIET AND INSULIN THERAPY IN WOMEN WITH GESTATIONAL DIABETES MELLITUS. JOURNAL OF MEDICAL COUNCIL OF I.R.I.[Internet]. 2006;23(4):355-361. Available from: https://sid.ir/paper/41005/en

IEEE: Copy

M. KESHAVARZ, GH.R. BABAEI, M.E. AJAMI, and M. DELVARIANZADEH, “COMPARISON OF PREGNANCY COMPLICATIONS BETWEEN GROUPS WITH DIET AND INSULIN THERAPY IN WOMEN WITH GESTATIONAL DIABETES MELLITUS,” JOURNAL OF MEDICAL COUNCIL OF I.R.I., vol. 23, no. 4, pp. 355–361, 2006, [Online]. Available: https://sid.ir/paper/41005/en

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