COMPARISON BETWEEN THE EFFECT OF AMITRIPTYLINE AND NORTRIPTYLINE ON THE TREATMENT OF DIARRHEA DOMINANT IBS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GHADIR M.R.; KHADEMI H.; BAKHSHIPOUR A.; BAGHERI M.; ABBASIAN A.; ADELI S.H.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Medical Council of Iran Year:2008 | Volume:25 | Issue:4 Page(s): 421-430

Download Full-Text

Persian Verion

View:

1,282

Download:

Cites:

Information Journal Paper

Title

COMPARISON BETWEEN THE EFFECT OF AMITRIPTYLINE AND NORTRIPTYLINE ON THE TREATMENT OF DIARRHEA DOMINANT IBS

Author(s)

Keywords

IRRITABLE BOWEL SYNDROMEQ2

AMITRIPTYLINEQ3

ORTRIPTYLINEQ3

Abstract

Background: IRRITABLE BOWEL SYNDROME (IBS) is one of the most common GI problems and almost one-fourth of all patients who visit a gastroenterologist have this complaint. There are several controlled studies about the effect of some antidepressants on the treatment of IBS compared to placebo. However, few studies have compared the effect of antidepressant drugs with each other. This study compared the effect of AMITRIPTYLINE and nortriptyline on the treatment of IBS. Methods: A total of 60 patients with diarrhea dominant IBS diagnosed using Rome II questionnaire enrolled in this study. We ruled out organic causes with taking history of diseases for each patient and doing some related lab tests such as celiac tests. We randomly divided these patients into two groups (Group 1; 10 mg AMITRIPTYLINE, Group2; 10 mg nortriptyline). All the symptoms were recorded at the beginning of the study, after one month and finally after 3 months from beginning of the treatment.Findings: We observed a significant relief of symptoms in both groups at the end of first month and also third month of treatment.The overall symptoms' relief changed from 49% to 9% in AMITRIPTYLINE group and from 52% to 8% in nortriptyline group at the end of third month.Conclusion: Either amitryptyline or nortriptyline are effective drugs in the treatment of diarrhea dominant IBS and there is no significant difference between their effect on this group of patients.

Cites

No record.

References

No record.

Cite

APA: Copy

GHADIR, M.R., KHADEMI, H., BAKHSHIPOUR, A., BAGHERI, M., ABBASIAN, A., & ADELI, S.H.. (2008). COMPARISON BETWEEN THE EFFECT OF AMITRIPTYLINE AND NORTRIPTYLINE ON THE TREATMENT OF DIARRHEA DOMINANT IBS. JOURNAL OF MEDICAL COUNCIL OF I.R.I., 25(4), 421-430. SID. https://sid.ir/paper/41026/en

Vancouver: Copy

GHADIR M.R., KHADEMI H., BAKHSHIPOUR A., BAGHERI M., ABBASIAN A., ADELI S.H.. COMPARISON BETWEEN THE EFFECT OF AMITRIPTYLINE AND NORTRIPTYLINE ON THE TREATMENT OF DIARRHEA DOMINANT IBS. JOURNAL OF MEDICAL COUNCIL OF I.R.I.[Internet]. 2008;25(4):421-430. Available from: https://sid.ir/paper/41026/en

IEEE: Copy

M.R. GHADIR, H. KHADEMI, A. BAKHSHIPOUR, M. BAGHERI, A. ABBASIAN, and S.H. ADELI, “COMPARISON BETWEEN THE EFFECT OF AMITRIPTYLINE AND NORTRIPTYLINE ON THE TREATMENT OF DIARRHEA DOMINANT IBS,” JOURNAL OF MEDICAL COUNCIL OF I.R.I., vol. 25, no. 4, pp. 421–430, 2008, [Online]. Available: https://sid.ir/paper/41026/en

Related Journal Papers