PATHOLOGICAL EVALUATION AND THE NEW CLASSIFICATION OF UTERINE SMOOTH MUSCLE TUMORS

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IZADI MOUD N.; SHAYANFAR N.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Journal of Medical Council of Iran Year:2003 | Volume:21 | Issue:2 Page(s): 101-105

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Title

PATHOLOGICAL EVALUATION AND THE NEW CLASSIFICATION OF UTERINE SMOOTH MUSCLE TUMORS

Author(s)

IZADI MOUD N. | SHAYANFAR N. | Issue Writer Certificate

Keywords

LEIOMYOMAQ3

LEIOMYOSARCOMAQ4

COAGULATIVE TUMOR CELL NECROSISQ4

MITOSISQ4

CELLULAR ATYPIAQ4

Abstract

There exists controversies in the classification of uterine smooth muscle tumors (SMTS). The number of mitotic figures in 10 hpf in the most active areas (mitotic index) was used as the most common diagnostic criterion to evaluate malignancy (Taylor &Norris classification, 1966), mitotic index and CELLULAR ATYPIA (Zalondek & Norris ,1981). Accordingly when there were more than 10 MITOSIS per 10 hpf, it was classified as malignant lesion but experiences have shown that not all SMTS with more than 10 mitoses per 10 hpf are malignant, so it nesseciates reevaluation and using other differentiating criteria. Bell and Colleagues (1995) have used COAGULATIVE TUMOR CELL NECROSIS (CTCN) and degree of CELLULAR ATYPIA to classify SMTS into five groups.In this article, we reevaluated SMTS in Mirza Kouchak Khan hospital which were previously diagnosed based on Taylor and Norris classification) between 1994-1998, using mitotic index, degree of CELLULAR ATYPIA and CTCN (Bell classification) as three defining criteria. Overall 612 SMTS were reevaluated and subclassified as:Group I: 603 cases, Group II:2 cases, Group III: 6 cases, Group IV: No case and Group V: 1 case.In this study diagnosis was changed in three cases, with the new classification muscle tumor of uncertain malignant potential (STUMP), and one case of LEIOMYOSARCOMA were changed to the LEIOMYOMA. The third case of LEIOMYOMA was changed to the atypical LEIOMYOMA with limited experience.

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APA: Copy

IZADI MOUD, N., & SHAYANFAR, N.. (2003). PATHOLOGICAL EVALUATION AND THE NEW CLASSIFICATION OF UTERINE SMOOTH MUSCLE TUMORS. JOURNAL OF MEDICAL COUNCIL OF I.R.I., 21(2), 101-105. SID. https://sid.ir/paper/41179/en

Vancouver: Copy

IZADI MOUD N., SHAYANFAR N.. PATHOLOGICAL EVALUATION AND THE NEW CLASSIFICATION OF UTERINE SMOOTH MUSCLE TUMORS. JOURNAL OF MEDICAL COUNCIL OF I.R.I.[Internet]. 2003;21(2):101-105. Available from: https://sid.ir/paper/41179/en

IEEE: Copy

N. IZADI MOUD, and N. SHAYANFAR, “PATHOLOGICAL EVALUATION AND THE NEW CLASSIFICATION OF UTERINE SMOOTH MUSCLE TUMORS,” JOURNAL OF MEDICAL COUNCIL OF I.R.I., vol. 21, no. 2, pp. 101–105, 2003, [Online]. Available: https://sid.ir/paper/41179/en

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