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Information Journal Paper

Title

Effect of Hydroalcoholic Extract of Lavender on Apoptosis of Liver Cancer Cells (HepG2)

Pages

  177-183

Keywords

Hepatic Cancer (HepG2)Q1

Abstract

 Aims Despite many advances in cancer treatment and control, significant deficiencies remain and the rate of cancer growth is increasing. Due to the side effects of using chemicals and radiation, the use of herbs can have fewer side effects for the patient. The aim of the current study is to investigate the potential anticancer effects of alcoholic extract of Lavender on inhibition and growth of HepG2 cell lines. Materials & Methods In this study, the effect of alcoholic extract of Lavender (1, 10, 100, and 1000μ g/ml) on HepG2 liver cancer cell line was studied. MTT assay was used to evaluate the toxicity of Lavender extract and cell viability. Cell Cycle changes were assessed using a flow cytometer. Oxygen-free species production and membrane lipid peroxidation were also measured. Findings The results showed that alcoholic extract of Lavender has anticancer effect on HepG2 cell line. After confirming the effect of Lavender extract on Cell Cycle, the results obtained from the evaluation of membrane lipid peroxidation and production of free reactive species were also significant. Conclusion According to the results of this study, the alcoholic extract of Lavender was reported as a potential anticancer agent and is one of the therapeutic strategies in liver cancer.

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    Cite

    APA: Copy

    REZAEI, M., & Rajabbeigi, E.. (2020). Effect of Hydroalcoholic Extract of Lavender on Apoptosis of Liver Cancer Cells (HepG2). PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES), 23(4 ), 177-183. SID. https://sid.ir/paper/412026/en

    Vancouver: Copy

    REZAEI M., Rajabbeigi E.. Effect of Hydroalcoholic Extract of Lavender on Apoptosis of Liver Cancer Cells (HepG2). PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES)[Internet]. 2020;23(4 ):177-183. Available from: https://sid.ir/paper/412026/en

    IEEE: Copy

    M. REZAEI, and E. Rajabbeigi, “Effect of Hydroalcoholic Extract of Lavender on Apoptosis of Liver Cancer Cells (HepG2),” PATHOBIOLOGY RESEARCH (MODARES JOURNAL OF MEDICAL SCIENCES), vol. 23, no. 4 , pp. 177–183, 2020, [Online]. Available: https://sid.ir/paper/412026/en

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