THE STUDY OF CARCINOGENICITY TEST (AMES TEST) IN FORENSIC MEDICINE LABORATORIES OF TEHRAN AND COMPARISON WITH TEHRAN UNIVERSITY MEDICAL SCIENCES LABORATORIES

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PARTOU AZAR A.R.; ABEDI M.H.; GHAZI KHANSARI M.; BASIRI M.R.; KAVIANI MAHDI

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Journal: Journal of Medical Council of Iran Year:2009 | Volume:27 | Issue:2 Page(s): 212-218

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Title

THE STUDY OF CARCINOGENICITY TEST (AMES TEST) IN FORENSIC MEDICINE LABORATORIES OF TEHRAN AND COMPARISON WITH TEHRAN UNIVERSITY MEDICAL SCIENCES LABORATORIES

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AMES TESTQ3

CARCINOGENICITYQ4

FORENSIC MEDICINEQ3

PATHOLOGY LABORATORYQ3

Abstract

Background: cancer is one of the most frequent diseases in the world and mutation has an important role in etiology of cancer (approximately 90% of mutagens are carcinogen). Therefore Lab assistances that are working with mutagenic agents such as: Benzene, Xylazine and Formaldehyde for long period of time may be exposed to overload of these carcinogens. In Previous study, Muatgenicity test on urine sample of laboratory pathology technician of Tehran university medical sciences determined mutagenic agent’s activity. In regards to results, Mutagenicity assay was considered on FORENSIC MEDICINE laboratory of Tehran.Methods: Urine samples were collected at the end of the work shift and then were extracted by c18 column for the maximum concentration of pollutants. Then extracts were tested by TA100 and TA98 standard strains as well both with and without metabolic activator.Results: Levels of toxicity and mutagen city were detected by TA98 strain with activator in two personnel of pathology lab.Conclusion: Our result shows that FORENSIC MEDICINE pathology lab. worker have the same risk of cancer as the TUMS pathology lab. personals. I loecause smoking and other confounding factories not recorder false positive result is probably disregarded in this study.

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APA: Copy

PARTOU AZAR, A.R., ABEDI, M.H., GHAZI KHANSARI, M., BASIRI, M.R., & KAVIANI, MAHDI. (2009). THE STUDY OF CARCINOGENICITY TEST (AMES TEST) IN FORENSIC MEDICINE LABORATORIES OF TEHRAN AND COMPARISON WITH TEHRAN UNIVERSITY MEDICAL SCIENCES LABORATORIES. JOURNAL OF MEDICAL COUNCIL OF I.R.I., 27(2), 212-218. SID. https://sid.ir/paper/41344/en

Vancouver: Copy

PARTOU AZAR A.R., ABEDI M.H., GHAZI KHANSARI M., BASIRI M.R., KAVIANI MAHDI. THE STUDY OF CARCINOGENICITY TEST (AMES TEST) IN FORENSIC MEDICINE LABORATORIES OF TEHRAN AND COMPARISON WITH TEHRAN UNIVERSITY MEDICAL SCIENCES LABORATORIES. JOURNAL OF MEDICAL COUNCIL OF I.R.I.[Internet]. 2009;27(2):212-218. Available from: https://sid.ir/paper/41344/en

IEEE: Copy

A.R. PARTOU AZAR, M.H. ABEDI, M. GHAZI KHANSARI, M.R. BASIRI, and MAHDI KAVIANI, “THE STUDY OF CARCINOGENICITY TEST (AMES TEST) IN FORENSIC MEDICINE LABORATORIES OF TEHRAN AND COMPARISON WITH TEHRAN UNIVERSITY MEDICAL SCIENCES LABORATORIES,” JOURNAL OF MEDICAL COUNCIL OF I.R.I., vol. 27, no. 2, pp. 212–218, 2009, [Online]. Available: https://sid.ir/paper/41344/en

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