The Effect of Eight Weeks of High-Intensity Interval Training and Endurance On Blood Glucose and TORC1 Protein Content in Subcutaneous Adipose Tissue of Obese with Type 2 Diabetes Rats

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Hosseini Seyedeh Sogand; Esmaelzadeh Toloee Mohammedreza

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Journal: Iranian Journal of Diabetes and Metabolism Year:2021 | Volume:21 | Issue:1 Page(s): 39-48

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Title

The Effect of Eight Weeks of High-Intensity Interval Training and Endurance On Blood Glucose and TORC1 Protein Content in Subcutaneous Adipose Tissue of Obese with Type 2 Diabetes Rats

Author(s)

Hosseini Seyedeh Sogand | Esmaelzadeh Toloee Mohammedreza | Issue Writer Certificate

Keywords

Blood GlucoseQ2

Endurance TrainingQ1

High-Intensity Interval TrainingQ1

Subcutaneous Adipose TissueQ1

TORC1 ProteinQ1

Type 2 DiabetesQ1

Abstract

Background: TORC1 Protein is an important factor in regulating adipose tissue metabolism. Type 2 Diabetes can lead to dysfunction and the development of obesity. Therefore, the aim of the present study was to investigate the effect of eight weeks of High-Intensity Interval Training (HIIT) and endurance on Blood Glucose and TORC1 Protein content in Subcutaneous Adipose Tissue of obese with Type 2 Diabetes rats. Methods: In this study, 18 head 2 Sprague-Dawley male rats with a mean weight of 270± 30 g were selected. After becoming type 1 diabetic through streptozotocin and Nicotine amide solution, they were randomly divided into 3 groups: 1) HIIT training 2) Endurance Training and 3) control (6 heads per group). Exercise groups exercised 4 days a week for 8 weeks according to HIIT and Endurance Training programs. SPSS software version 23, one-way ANOVA and Tukey post hoc test were used to analyze the data. Result: Eight weeks of HIIT and Endurance Training resulted in a significant decrease in Blood Glucose level (p<0. 0001) and a significant increase in TORC1 Protein content (P<0. 0001) compared to the control group. Conclusion: HIIT and Endurance Training lowered Blood Glucose levels and increase TORC1 Protein content, which this training can be a suitable and non-invasive treatment to control diabetes and also regulate adipose tissue metabolism in type 2 diabetics who are prone to obesity.

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APA: Copy

Hosseini, Seyedeh Sogand, & Esmaelzadeh Toloee, Mohammedreza. (2021). The Effect of Eight Weeks of High-Intensity Interval Training and Endurance On Blood Glucose and TORC1 Protein Content in Subcutaneous Adipose Tissue of Obese with Type 2 Diabetes Rats. JOURNAL OF DIABETES AND METABOLIC DISORDERS, 21(1 ), 39-48. SID. https://sid.ir/paper/413467/en

Vancouver: Copy

Hosseini Seyedeh Sogand, Esmaelzadeh Toloee Mohammedreza. The Effect of Eight Weeks of High-Intensity Interval Training and Endurance On Blood Glucose and TORC1 Protein Content in Subcutaneous Adipose Tissue of Obese with Type 2 Diabetes Rats. JOURNAL OF DIABETES AND METABOLIC DISORDERS[Internet]. 2021;21(1 ):39-48. Available from: https://sid.ir/paper/413467/en

IEEE: Copy

Seyedeh Sogand Hosseini, and Mohammedreza Esmaelzadeh Toloee, “The Effect of Eight Weeks of High-Intensity Interval Training and Endurance On Blood Glucose and TORC1 Protein Content in Subcutaneous Adipose Tissue of Obese with Type 2 Diabetes Rats,” JOURNAL OF DIABETES AND METABOLIC DISORDERS, vol. 21, no. 1 , pp. 39–48, 2021, [Online]. Available: https://sid.ir/paper/413467/en

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