THE IMPORTANCE OF PRECISE MEASUREMENT OF HBF IN THE DIFFERENTIAL DIAGNOSIS OF SICKLE CELL ANEMIA FROM SICKLE BETA THALASSEMIA

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POURFATH ELAH A.A.; RAHGOZAR S.; MOAFI A.R.

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Journal: Journal of Medical Council of Iran Year:2003 | Volume:21 | Issue:1 Page(s): 51-54

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Title

THE IMPORTANCE OF PRECISE MEASUREMENT OF HBF IN THE DIFFERENTIAL DIAGNOSIS OF SICKLE CELL ANEMIA FROM SICKLE BETA THALASSEMIA

Author(s)

POURFATH ELAH A.A. | RAHGOZAR S. | MOAFI A.R. | Issue Writer Certificate

Keywords

SICKLE CELL ANEMIAQ3

SICKLE BETA THALASSEMIAQ4

FETAL HEMOGLOBIN (HBF)Q4

Abstract

SICKLE CELL ANEMIA, in heterozygous form, although appears to have a high incidence in Iran, particularly in the Southern provinces; unfortunately has not received the right attention and thus creating screening and prevention problems for haemoglobin disorders. Because of, laboratory and clinical similarities between, Indian Arad haplotype of SICKLE CELL ANEMIA which is estimated to have a high incidence in Iran, and, sickle beta talassaemina which is more frequent in this country, might cause diagnostic problems.In this article we present three cases with SICKLE CELL ANEMIA wich were diagnosed as sickle beta halassaemia. Eventually, we suggest determining haematological indices of patients parents and measuring HbF in suspected patients precisely by alkali denaturation, after the patient haemoglobin electrophoresis, to reduce incorrect diagnosis.

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APA: Copy

POURFATH ELAH, A.A., RAHGOZAR, S., & MOAFI, A.R.. (2003). THE IMPORTANCE OF PRECISE MEASUREMENT OF HBF IN THE DIFFERENTIAL DIAGNOSIS OF SICKLE CELL ANEMIA FROM SICKLE BETA THALASSEMIA. JOURNAL OF MEDICAL COUNCIL OF I.R.I., 21(1), 51-54. SID. https://sid.ir/paper/41362/en

Vancouver: Copy

POURFATH ELAH A.A., RAHGOZAR S., MOAFI A.R.. THE IMPORTANCE OF PRECISE MEASUREMENT OF HBF IN THE DIFFERENTIAL DIAGNOSIS OF SICKLE CELL ANEMIA FROM SICKLE BETA THALASSEMIA. JOURNAL OF MEDICAL COUNCIL OF I.R.I.[Internet]. 2003;21(1):51-54. Available from: https://sid.ir/paper/41362/en

IEEE: Copy

A.A. POURFATH ELAH, S. RAHGOZAR, and A.R. MOAFI, “THE IMPORTANCE OF PRECISE MEASUREMENT OF HBF IN THE DIFFERENTIAL DIAGNOSIS OF SICKLE CELL ANEMIA FROM SICKLE BETA THALASSEMIA,” JOURNAL OF MEDICAL COUNCIL OF I.R.I., vol. 21, no. 1, pp. 51–54, 2003, [Online]. Available: https://sid.ir/paper/41362/en

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