Determination of Total Antioxidant Capacity in Saliva of Smokers and Non-smokers with Chronic Periodontitis

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Mirzaei Ahmadreza; Mehrabani Natanzi Mahboobeh; KHODAII ZOHREH; Mirshamsi Hamid; RAFIEIAN NASRIN

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Journal: ALBORZ UNIVERSITY MEDICAL JOURNAL Year:2020 | Volume:9 | Issue:1 Page(s): 31-36

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Title

Determination of Total Antioxidant Capacity in Saliva of Smokers and Non-smokers with Chronic Periodontitis

Author(s)

Keywords

PeriodontitisQ2

CigaretteQ3

Total Antioxidant CapacityQ1

FRAPQ2

Abstract

Background: Periodontal diseases in smokers are 2. 6 to 6 times higher than non-smokers and their response to treatment is much lower. Reducing levels of antioxidants and consequently increasing oxidative damage in the pathogenesis of Periodontitis is effective. Regarding the importance of free radicals in the pathogenesis of periodontal diseases, the aim of this study was to investigate the effect of Cigarette on the oxidative and antioxidant status of saliva in chronic Periodontitis patients and compare it with healthy controls. Methods: In this case-control study, 20 patients with chronic Cigarette smoking Periodontitis, 20 patients with non-smoking chronic Periodontitis and 20 healthy individuals who had no history of Periodontitis and smoking, were among those referring to dental clinics and clinics of Karaj were chosen. Uninstivated saliva was collected and salivary Total Antioxidant Capacity was measured using a kit in saliva. Statistical analysis was performed using ANOVA. Results: Total Antioxidant Capacity of saliva in smoker Periodontitis and non-smoker Periodontitis was significantly (P <0. 05) less than normal Persons. Conclusion: Based on the results of this study, chronic Periodontitis reduces the Total Antioxidant Capacity of saliva, on the one hand, due to the increased production of oxidants in inflammatory responses to this disease, and, on the other hand, the presence of compounds such as nicotine Cigarette that disturbs the chain Respiratory mitochondria and increased oxidants.

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APA: Copy

Mirzaei, Ahmadreza, Mehrabani Natanzi, Mahboobeh, KHODAII, ZOHREH, Mirshamsi, Hamid, & RAFIEIAN, NASRIN. (2020). Determination of Total Antioxidant Capacity in Saliva of Smokers and Non-smokers with Chronic Periodontitis. ALBORZ UNIVERSITY MEDICAL JOURNAL, 9(1 ), 31-36. SID. https://sid.ir/paper/414783/en

Vancouver: Copy

Mirzaei Ahmadreza, Mehrabani Natanzi Mahboobeh, KHODAII ZOHREH, Mirshamsi Hamid, RAFIEIAN NASRIN. Determination of Total Antioxidant Capacity in Saliva of Smokers and Non-smokers with Chronic Periodontitis. ALBORZ UNIVERSITY MEDICAL JOURNAL[Internet]. 2020;9(1 ):31-36. Available from: https://sid.ir/paper/414783/en

IEEE: Copy

Ahmadreza Mirzaei, Mahboobeh Mehrabani Natanzi, ZOHREH KHODAII, Hamid Mirshamsi, and NASRIN RAFIEIAN, “Determination of Total Antioxidant Capacity in Saliva of Smokers and Non-smokers with Chronic Periodontitis,” ALBORZ UNIVERSITY MEDICAL JOURNAL, vol. 9, no. 1 , pp. 31–36, 2020, [Online]. Available: https://sid.ir/paper/414783/en

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