Effects of administration of biological silver nanoparticles during pregnancy on neonatal brain tissue of rats

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Yahyaei Behrooz; POURALI PARASTOO; AMERI FAEZEH

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Paper Information

Journal: Journal of Neyshabur University of Medical Sciences Year:2020 | Volume:8 | Issue:2 (27) Page(s): 95-106

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Information Journal Paper

Title

Effects of administration of biological silver nanoparticles during pregnancy on neonatal brain tissue of rats

Author(s)

Yahyaei Behrooz | POURALI PARASTOO | AMERI FAEZEH | Issue Writer Certificate

Keywords

NanoparticleQ1

ToxicQ1

NontoxicQ1

BrainQ2

Neonatal RatQ1

Abstract

Introduction Silver Nanoparticles are one of the most common Nanoparticles used in biomedical applications. They are made by two major chemical and biological methods. The aim of this study was to evaluate the changes of Brain tissue due to Toxic and non-toxic doses of biological silver Nanoparticles in Neonatal Rats. Materials and Methods This research was an experimental study and 18 male and female Wistar rats were selected and finally divided into 3 groups of 6. One control group and the rest were divided into two equal groups based on Toxic and non-toxic Nanoparticles. After the pregnancy, the injection was performed in the last two weeks of pregnancy. Two weeks after parturition, histological changes were observed under a microscope in the rats neonates' Brains. Results Histological specimens of the group receiving the Toxic dose of biological silver Nanoparticles show no significant change compared to the control group. Neurons and neuroglial cells had normal features, including clear nuclei and cytoplasm. Their cellular adhesions were also visible around them and no specific changes in neuropilia were observed. Conclusion The use of biological silver Nanoparticles in non-toxic and Toxic doses will not have a detrimental effect on Brain and tissue and cell morphological indicators.

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References

Histopathological study of the maternal exposure to the biologically produced silver nanoparticles on different organs of the offspring

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APA: Copy

Yahyaei, Behrooz, POURALI, PARASTOO, & AMERI, FAEZEH. (2020). Effects of administration of biological silver nanoparticles during pregnancy on neonatal brain tissue of rats. JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES, 8(2 (27) ), 95-106. SID. https://sid.ir/paper/416395/en

Vancouver: Copy

Yahyaei Behrooz, POURALI PARASTOO, AMERI FAEZEH. Effects of administration of biological silver nanoparticles during pregnancy on neonatal brain tissue of rats. JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;8(2 (27) ):95-106. Available from: https://sid.ir/paper/416395/en

IEEE: Copy

Behrooz Yahyaei, PARASTOO POURALI, and FAEZEH AMERI, “Effects of administration of biological silver nanoparticles during pregnancy on neonatal brain tissue of rats,” JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES, vol. 8, no. 2 (27) , pp. 95–106, 2020, [Online]. Available: https://sid.ir/paper/416395/en

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