The effect of 12 weeks of aerobic training on some selected inflammatory markers in cardiac tissue of male Wistar rats with two types of normal and cholesterol-rich feeding

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NASIRI MARYAM; ABBASSI DALOII ASIEH; BARARI ALIREZA; Saeidi Ayoub

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Journal: Journal of Jiroft University of Medical Sciences Year:2020 | Volume:7 | Issue:3 Page(s): 432-439

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Title

The effect of 12 weeks of aerobic training on some selected inflammatory markers in cardiac tissue of male Wistar rats with two types of normal and cholesterol-rich feeding

Author(s)

NASIRI MARYAM | ABBASSI DALOII ASIEH | BARARI ALIREZA | Saeidi Ayoub | Issue Writer Certificate

Keywords

Aerobic exercise

Inflammatory markers

Heart tissue

High cholesterol diet

Normal diet

Abstract

Introduction: Metabolic disorders induced by inactivity and malnutrition cause many problems in the Heart tissue. The aim of this study was to investigate the effect of 12 weeks Aerobic exercise on some selected Inflammatory markers in cardiac tissue of male Wistar rats with two types of normal and cholesterol-rich diet. Materials and Methods: In this experimental study, 40 male Wistar rats randomly divided into four groups of normal-control, normal-exercise, cholesterol-rich, cholesterol-The exercises were divided. The training groups performed 12 weeks (5 days a week) of endurance training and the control groups were kept in a cage for 12 weeks with no exercise. Prior to the beginning of the training period, the cholesterolrich diet group rats were fed this diet for three months to induce hyperlipidemia and dietary intervention was administered until the end of the training period. 48 hours after the last training session, they were killed after nocturnal fasting and then their blood and tissue samples were collected and measured. Results: Between groups analyses showed significant differences between different groups MCP-1 (p<0. 001), IL-6 (p<0. 001), TNF-α (P≤ 0. 05) and CK (p<0. 001), LDH (p<0. 001). Conclusion: According to the results of the study, moderate intensity Aerobic exercise may improve cardiac function and Inflammatory markers in individuals with normal and High cholesterol diet or even prevent cardiac tissue injury.

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APA: Copy

NASIRI, MARYAM, ABBASSI DALOII, ASIEH, BARARI, ALIREZA, & Saeidi, Ayoub. (2020). The effect of 12 weeks of aerobic training on some selected inflammatory markers in cardiac tissue of male Wistar rats with two types of normal and cholesterol-rich feeding. JOURNAL OF JIROFT UNIVERSITY OF MEDICAL SCIENCES, 7(3 ), 432-439. SID. https://sid.ir/paper/416525/en

Vancouver: Copy

NASIRI MARYAM, ABBASSI DALOII ASIEH, BARARI ALIREZA, Saeidi Ayoub. The effect of 12 weeks of aerobic training on some selected inflammatory markers in cardiac tissue of male Wistar rats with two types of normal and cholesterol-rich feeding. JOURNAL OF JIROFT UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;7(3 ):432-439. Available from: https://sid.ir/paper/416525/en

IEEE: Copy

MARYAM NASIRI, ASIEH ABBASSI DALOII, ALIREZA BARARI, and Ayoub Saeidi, “The effect of 12 weeks of aerobic training on some selected inflammatory markers in cardiac tissue of male Wistar rats with two types of normal and cholesterol-rich feeding,” JOURNAL OF JIROFT UNIVERSITY OF MEDICAL SCIENCES, vol. 7, no. 3 , pp. 432–439, 2020, [Online]. Available: https://sid.ir/paper/416525/en

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