EFFECTS OF VITAMIN AND MINERAL SUPPLEMENTS ON MICROALBUMINURIA AND N-ACETYL-β -D-GLUCOSAMINIDASE ACTIVITY (-βNAG) IN TYPE 2 DIABETIC PATIENTS

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FARVID M.A.S.; JALALI M.; SIASI F.; CHAMARI M.

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Journal: Research in Medicine Year:2006 | Volume:30 | Issue:1 Page(s): 17-24

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Information Journal Paper

Title

EFFECTS OF VITAMIN AND MINERAL SUPPLEMENTS ON MICROALBUMINURIA AND N-ACETYL-β -D-GLUCOSAMINIDASE ACTIVITY (-βNAG) IN TYPE 2 DIABETIC PATIENTS

Author(s)

FARVID M.A.S. | JALALI M. | SIASI F. | CHAMARI M. | Issue Writer Certificate

Keywords

VITAMIN CQ2

VITAMINEQ3

MAGNESIUMQ3

ZINCQ3

MICOALBUMINURIAQ3

βNAGQ3

Abstract

Background: The present study was designed to assess the effect of Mg, Zn, VITAMIN C and E supplements on microalbuminuria and urinary albumin excretion and N-acetyl-b-D-glucosaminidase activity (bNAG) in type 2 diabetic patients.Materials and methods: In a randomized, double-blind, placebo controlled clinical trial, 69 type 2 diabetic patients were randomly divided into four groups and received one of the following daily supplement for 3 months; group M: 200 mg Mg and 30 mg Zn (n=16), group V: 200 mg VITAMIN C and 100 IV vitamin E (n=18), group MV: minerals plus vitamins (n=17), group P: placebo (n=18). Serum malondialdehyde concentration as well as urine microalbumin concentration and bNAG activity and blood pressure were measured at the baseline and following the intervention.Results: Results have revealed that following the intervention urinary albumin decreased in V and MY groups. Vrinary bNAG activity and protein concentration did not change significantly; however, malondialdehyde concentration was significantly decreased in M and MV groups. Finally, systolic, diastolic and mean blood pressure decreased significantly in the MV group.Conclusion: Our findings indicate that a combination of vitamin and mineral could decrease urinary concentration of microalbumin in type 2 diabetic patients. Thus, these supplements could be prescribed to improve renal function in type 2 diabetic patients.

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References

IMPACT OF VITAMIN AND/OR MINERAL SUPPLEMENTATION ON LIPID PROFILES IN TYPE 2 DIABETES

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APA: Copy

FARVID, M.A.S., JALALI, M., SIASI, F., & CHAMARI, M.. (2006). EFFECTS OF VITAMIN AND MINERAL SUPPLEMENTS ON MICROALBUMINURIA AND N-ACETYL-β -D-GLUCOSAMINIDASE ACTIVITY (-βNAG) IN TYPE 2 DIABETIC PATIENTS. PAJOUHESH DAR PEZESHKI, 30(1), 17-24. SID. https://sid.ir/paper/41914/en

Vancouver: Copy

FARVID M.A.S., JALALI M., SIASI F., CHAMARI M.. EFFECTS OF VITAMIN AND MINERAL SUPPLEMENTS ON MICROALBUMINURIA AND N-ACETYL-β -D-GLUCOSAMINIDASE ACTIVITY (-βNAG) IN TYPE 2 DIABETIC PATIENTS. PAJOUHESH DAR PEZESHKI[Internet]. 2006;30(1):17-24. Available from: https://sid.ir/paper/41914/en

IEEE: Copy

M.A.S. FARVID, M. JALALI, F. SIASI, and M. CHAMARI, “EFFECTS OF VITAMIN AND MINERAL SUPPLEMENTS ON MICROALBUMINURIA AND N-ACETYL-β -D-GLUCOSAMINIDASE ACTIVITY (-βNAG) IN TYPE 2 DIABETIC PATIENTS,” PAJOUHESH DAR PEZESHKI, vol. 30, no. 1, pp. 17–24, 2006, [Online]. Available: https://sid.ir/paper/41914/en

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