PREOPERATIVE CLONIDINE IN PREVENTING OCULAR HYPERTENSION

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ROUHANI M.R.; BORJIAN D.; ERFANIAN SALIM R.

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Journal: BINA Year:2003 | Volume:8 | Issue:4 (32) Page(s): 334-340

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Information Journal Paper

Title

PREOPERATIVE CLONIDINE IN PREVENTING OCULAR HYPERTENSION

Author(s)

ROUHANI M.R. | BORJIAN D. | ERFANIAN SALIM R. | Issue Writer Certificate

Keywords

CLONIDINEQ3

INTRAOCULAR PRESSUREQ3

CATARACT SURGERYQ3

Abstract

Purpose: To evaluate the efficacy of preoperative oral CLONIDINE (5 µg/kg) in preventing ocular hypertension in the early period after CATARACT SURGERY with posterior chamber intraocular lens implantation under general anesthesia.Methods: This randomized double-masked clinical trial comprised 62 eyes of 62 patients with senile cataract who underwent cataract extraction and posterior chamber intraocular lens implantation without any viscoelastic use. They were randomly assigned into two groups of preoperative oral CLONIDINE (5 µg/kg) and placebo. INTRAOCULAR PRESSURE (lOP) was measured preoperatively and 6, 12, and 24 hours postoperatively. Results: There was less increase in mean lOP in the CLONIDINE group at 6 hours (+0.41±4.55, P=0.6) and 12 hours (0.06±3.62, P=0.9) compared to the placebo group (5.77±4.25, P=<0.001 and 4.70±3.19,P<0.001,respectively) after surgery. There was no statistically significant difference between the two groups in mean lOP 24 hours post operatively (CLONIDINE group 15.41±3.96, placebo group 16.00±341) but compared to preoperative lOP, less increase in mean lOP was seen in the CLONIDINE group (1.38±4.64, P=0.1 as compared to the placebo group (+3.80±2.92, P<0.001).Conclusion: A single dose of oral CLONIDINE (5 µg/kg) preoperatively can produce a significant lOP-lowering effect in the early period after CATARACT SURGERY, especially in the first 12 hours.

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APA: Copy

ROUHANI, M.R., BORJIAN, D., & ERFANIAN SALIM, R.. (2003). PREOPERATIVE CLONIDINE IN PREVENTING OCULAR HYPERTENSION. BINA, 8(4 (32)), 334-340. SID. https://sid.ir/paper/42551/en

Vancouver: Copy

ROUHANI M.R., BORJIAN D., ERFANIAN SALIM R.. PREOPERATIVE CLONIDINE IN PREVENTING OCULAR HYPERTENSION. BINA[Internet]. 2003;8(4 (32)):334-340. Available from: https://sid.ir/paper/42551/en

IEEE: Copy

M.R. ROUHANI, D. BORJIAN, and R. ERFANIAN SALIM, “PREOPERATIVE CLONIDINE IN PREVENTING OCULAR HYPERTENSION,” BINA, vol. 8, no. 4 (32), pp. 334–340, 2003, [Online]. Available: https://sid.ir/paper/42551/en

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