EFFECTS OF ORAL TRANEXAMIC ACID VS ORAL PREDNISOLONE ON REBLEEDING IN TRAUMATIC HYPHEMA

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SAMAVATI M.; AKBARZADEH S.; MANI KASHANI KH.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: BINA Year:2006 | Volume:12 | Issue:1 (46) Page(s): 64-69

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Title

EFFECTS OF ORAL TRANEXAMIC ACID VS ORAL PREDNISOLONE ON REBLEEDING IN TRAUMATIC HYPHEMA

Author(s)

SAMAVATI M. | AKBARZADEH S. | MANI KASHANI KH. | Issue Writer Certificate

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Abstract

Purpose: To evaluate the effect of oral tranexamic acid, oral prednisolone and placebo on prevention of recurrent hemorrhage in traumatic hyphema.Methods: This randomized placebo-controlled double-blind clinical trial was performed on 182 subjects affected by hyphema after blunt trauma. The patients were hospitalized for at least 5 days and were randomly assigned for receiving oral tranexamicacid (75mg/kg/day; 3 divided doses), oralprednisolone (0.8mg/kg/day; 2 divided doses) and oral placebo (3 times a day). Recurrent hemorrhage was measured during the course of hospitalization.Results: Rebleeding was significantly more frequent in the placebo group (26.7%) versus the prednisolone (15.0%) and tranexamic acid (13.3%) groups (P=0.0032%), but there was no statistically significant difference between the two latter groups.Conclusion: There is no significant difference between oral prednisolone and tranexamic acid in reducing the rate of rebreeding in traumatic hyphema.

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APA: Copy

SAMAVATI, M., AKBARZADEH, S., & MANI KASHANI, KH.. (2006). EFFECTS OF ORAL TRANEXAMIC ACID VS ORAL PREDNISOLONE ON REBLEEDING IN TRAUMATIC HYPHEMA. BINA, 12(1 (46)), 64-69. SID. https://sid.ir/paper/42610/en

Vancouver: Copy

SAMAVATI M., AKBARZADEH S., MANI KASHANI KH.. EFFECTS OF ORAL TRANEXAMIC ACID VS ORAL PREDNISOLONE ON REBLEEDING IN TRAUMATIC HYPHEMA. BINA[Internet]. 2006;12(1 (46)):64-69. Available from: https://sid.ir/paper/42610/en

IEEE: Copy

M. SAMAVATI, S. AKBARZADEH, and KH. MANI KASHANI, “EFFECTS OF ORAL TRANEXAMIC ACID VS ORAL PREDNISOLONE ON REBLEEDING IN TRAUMATIC HYPHEMA,” BINA, vol. 12, no. 1 (46), pp. 64–69, 2006, [Online]. Available: https://sid.ir/paper/42610/en

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