MANUFACTURING, QUALITY ASSURANCE PROCEDURES, AND ENFORCEMENT OF ANIMAL PHASE OF OCULAR I125 RADIOACTIVE PLAQUES

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SHEYBANI S.; POORBEIGI H.; GHASEMI F.; JAVANSHIR M.R.; MORADI S.; ARJMAND M.; SADEGHI TARI A.; KARKHANEH R.; JABARVAND M.; LASHEI A.R.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: BINA Year:2016 | Volume:21 | Issue:3 (84) Page(s): 208-217

Download Full-Text

Persian Verion

View:

752

Download:

Cites:

Information Journal Paper

Title

MANUFACTURING, QUALITY ASSURANCE PROCEDURES, AND ENFORCEMENT OF ANIMAL PHASE OF OCULAR I125 RADIOACTIVE PLAQUES

Author(s)

Keywords

BRACHYTHERAPYQ3

CHOROIDAL MELANOMAQ3

IODIDE 125Q3

RADIOACTIVEQ3

Abstract

Purpose: To design and manufacture Iodine 125 RADIOACTIVE plaques which can be used in patients with ocular melanoma, and to evaluate the efficacy of plaques in an animal model.Methods: This prospective basic study was performed in collaboration with Farabi hospital and Tehran atomic energy agency. The IODIDE 125 plaques were designed and manufactured based on the Collaborative Ocular Melanoma Study (COMS) designation rules.Results: The plaques were manufactured from gold according to the COMS designation rules. Each plaque contained a layer of Iodine 125 particles with an approximate activity of 5 millicurie for each particle. The radiation dosimetry was performed using radiochromic films (HD-810) and film scanner and Osiris software. The results indicated that the absorbed dose was along the central axis of the both manufactured phantoms. The results of the animal study revealed that the plaques had destructive effects of radiation on the retina, choroid and sclera of five rabbit eyes. The destructions were dose dependent and increased with the escalation of radiation dose.Conclusion: The I125 plaques manufactured in the present study had sufficient and dose dependent destructive effects on the retinal and choroidal structures of rabbit eyes in the implanted areas. These plaques were free from chemical toxicity.

Cites

No record.

References

DETERMINATION OF DOSIMETRIC CHARACTERISTICS OF IRSEED 125I BRACHYTHERAPY SOURCE

Cite

APA: Copy

SHEYBANI, S., POORBEIGI, H., GHASEMI, F., JAVANSHIR, M.R., MORADI, S., ARJMAND, M., SADEGHI TARI, A., KARKHANEH, R., JABARVAND, M., & LASHEI, A.R.. (2016). MANUFACTURING, QUALITY ASSURANCE PROCEDURES, AND ENFORCEMENT OF ANIMAL PHASE OF OCULAR I₁₂₅ RADIOACTIVE PLAQUES. BINA, 21(3 (84)), 208-217. SID. https://sid.ir/paper/42711/en

Vancouver: Copy

SHEYBANI S., POORBEIGI H., GHASEMI F., JAVANSHIR M.R., MORADI S., ARJMAND M., SADEGHI TARI A., KARKHANEH R., JABARVAND M., LASHEI A.R.. MANUFACTURING, QUALITY ASSURANCE PROCEDURES, AND ENFORCEMENT OF ANIMAL PHASE OF OCULAR I₁₂₅ RADIOACTIVE PLAQUES. BINA[Internet]. 2016;21(3 (84)):208-217. Available from: https://sid.ir/paper/42711/en

IEEE: Copy

S. SHEYBANI, H. POORBEIGI, F. GHASEMI, M.R. JAVANSHIR, S. MORADI, M. ARJMAND, A. SADEGHI TARI, R. KARKHANEH, M. JABARVAND, and A.R. LASHEI, “MANUFACTURING, QUALITY ASSURANCE PROCEDURES, AND ENFORCEMENT OF ANIMAL PHASE OF OCULAR I₁₂₅ RADIOACTIVE PLAQUES,” BINA, vol. 21, no. 3 (84), pp. 208–217, 2016, [Online]. Available: https://sid.ir/paper/42711/en

Related Journal Papers