FREQUENCY OF METABOLIC SYNDROME IN MALE PATIENTS WITH RHEUMATOID ARTHRITIS: A CROSS-SECTIONAL STUDY

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SADR SARA; DASHTI DARGAHLOO SAEED; NIKSOLAT FATEMEH; HOSEINIAN AREF; MOBINI MARYAM; KARIMI MARYAM

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Journal: Journal of Mazandaran University of Medical Sciences Year:2018 | Volume:27 | Issue:158 Page(s): 101-111

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Title

FREQUENCY OF METABOLIC SYNDROME IN MALE PATIENTS WITH RHEUMATOID ARTHRITIS: A CROSS-SECTIONAL STUDY

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Keywords

METABOLIC SYNDROMEQ2

RHEUMATOID ARTHRITISQ3

INFLAMMATIONQ2

MENQ2

Abstract

Background and purpose: RHEUMATOID ARTHRITIS (RA) is an autoimmune disease that increasethe risk of coronary artery diseases. METABOLIC SYNDROME (MetS) is considered as a risk factor fordeveloping coronary artery diseases. There are some concerns about the association between RA andMetS, therefore, this study was done to evaluate the prevalence of MetS in male RA patients. Materials and methods: In a cross sectional study, male RA patients (n= 50) were evaluatedregarding demographic and clinical features including disease activity score 28 (DAS28), healthassessment questionnaire (HAQ), visual analogue scale (VAS), and laboratory parameters and comparedwith 50 age-matched controls. MetS was diagnosed according to the 2005 National Cholesterol EducationProgram Adult Treatment Panel III (NCEP/ATP III) and International Diabetes Federation (IDF)definition. The prevalence of MetS was compared in RA patients and controls. Statistical analysis wasperformed in SPSS V19, and results were considered significant at P< 0. 05. Results: The mean ages of RA patients and controls were 49. 04± 10. 2 and 46. 12± 9. 4 years, respectively (P= 0. 139). MetS according to NCEP and IDF criteria was present in 12 (24%) and 18 (36%)of RA patients vs 16 (32%) and 18 (36%) of controls, respectively that was not significantly different. Controls were more likely to have hyperglycemia and hypercholesterolemia, especially higher levels oflow density lipoprotein (P<0. 05). Conclusion: According to the present study, prevalence of MetS was similar in RA patients andcontrols. MetS components should be routinely investigated in male RA patients to reduce the occurrenceof MetS and its complications.

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APA: Copy

SADR, SARA, DASHTI DARGAHLOO, SAEED, NIKSOLAT, FATEMEH, HOSEINIAN, AREF, MOBINI, MARYAM, & KARIMI, MARYAM. (2018). FREQUENCY OF METABOLIC SYNDROME IN MALE PATIENTS WITH RHEUMATOID ARTHRITIS: A CROSS-SECTIONAL STUDY. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 27(158 ), 101-111. SID. https://sid.ir/paper/44185/en

Vancouver: Copy

SADR SARA, DASHTI DARGAHLOO SAEED, NIKSOLAT FATEMEH, HOSEINIAN AREF, MOBINI MARYAM, KARIMI MARYAM. FREQUENCY OF METABOLIC SYNDROME IN MALE PATIENTS WITH RHEUMATOID ARTHRITIS: A CROSS-SECTIONAL STUDY. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;27(158 ):101-111. Available from: https://sid.ir/paper/44185/en

IEEE: Copy

SARA SADR, SAEED DASHTI DARGAHLOO, FATEMEH NIKSOLAT, AREF HOSEINIAN, MARYAM MOBINI, and MARYAM KARIMI, “FREQUENCY OF METABOLIC SYNDROME IN MALE PATIENTS WITH RHEUMATOID ARTHRITIS: A CROSS-SECTIONAL STUDY,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 158 , pp. 101–111, 2018, [Online]. Available: https://sid.ir/paper/44185/en

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