AN OVERVIEW OF ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS; DIAGNOSTIC AND THERAPEUTIC ASPECTS

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AFSARIAN MOHAMMAD HOSEIN; MORADI FATEMEH; Kouhpayeh Seyed Amin; Ataollahi Mohammad Reza; FARZANEHPOOR ANGELLA; Fakhim Hamed; KHODAVAISY SADEGH; BADALI HAMID

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Journal: Journal of Mazandaran University of Medical Sciences Year:2016 | Volume:26 | Issue:138 Page(s): 232-248

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Title

AN OVERVIEW OF ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS; DIAGNOSTIC AND THERAPEUTIC ASPECTS

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Keywords

ABPAQ1

ASTHMAQ3

ASPERGILLUS SPECIESQ2

IGEQ3

Abstract

Allergic Bronchopulmonary Aspergillosis (ABPA) is a hypersensitivity response to Aspergillus antigens in patients with ASTHMA or cystic fibrosis (CF). The inhalation of spores from the environment is followed by growth of hyphae in the mucus of the bronchial tree and stimulates an immune response involving Th2 CD4+ T cells and IGE and IgG antibodies. Although diagnostic procedure for ABPA is a big challenge, serological marker (measurement of IGE antibody) for the diagnosis of ABPA is chosen in clinical. However, cross-reactivity may also occur between crude fungal extracts. Therefore, combination of clinical, biological and radiological criteria with molecular-based allergy can solve this problem. Although, the mainstay of treatment for ABPA is corticosteroids followed by antifungal regimes, but treatment is dependent on the ABPA stage with ASTHMA control, prevention and treatment of acute disease, and preventing the progression of bronchiectasis. The current review paper presents a comprehensive overview of the allergic bronchopulmonary aspergillosis based on diagnostic and therapeutic aspects.

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APA: Copy

AFSARIAN, MOHAMMAD HOSEIN, MORADI, FATEMEH, Kouhpayeh, Seyed Amin, Ataollahi, Mohammad Reza, FARZANEHPOOR, ANGELLA, Fakhim, Hamed, KHODAVAISY, SADEGH, & BADALI, HAMID. (2016). AN OVERVIEW OF ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS; DIAGNOSTIC AND THERAPEUTIC ASPECTS. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 26(138), 232-248. SID. https://sid.ir/paper/44232/en

Vancouver: Copy

AFSARIAN MOHAMMAD HOSEIN, MORADI FATEMEH, Kouhpayeh Seyed Amin, Ataollahi Mohammad Reza, FARZANEHPOOR ANGELLA, Fakhim Hamed, KHODAVAISY SADEGH, BADALI HAMID. AN OVERVIEW OF ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS; DIAGNOSTIC AND THERAPEUTIC ASPECTS. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2016;26(138):232-248. Available from: https://sid.ir/paper/44232/en

IEEE: Copy

MOHAMMAD HOSEIN AFSARIAN, FATEMEH MORADI, Seyed Amin Kouhpayeh, Mohammad Reza Ataollahi, ANGELLA FARZANEHPOOR, Hamed Fakhim, SADEGH KHODAVAISY, and HAMID BADALI, “AN OVERVIEW OF ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS; DIAGNOSTIC AND THERAPEUTIC ASPECTS,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 138, pp. 232–248, 2016, [Online]. Available: https://sid.ir/paper/44232/en

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