THE RELATIONSHIP BETWEEN DEVELOPING THALASSEMIA MAJOR AND DYSFUNCTION OF PANCREATIC ENDOCRINE AND EXOCRINE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KARAMI HASSAN; KOWSARIAN MEHRNOOSH; KARAMI HOSSAIN; KOWSARIAN SEYED SHAHAB; MAHDAVI MOHAMMAD REZA; DANESHMANDI ZAHRA; KHADEMLOO MOHAMMAD; SHAHMOHAMMADI SOHEILA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2011 | Volume:21 | Issue:83 Page(s): 1-7

Download Full-Text

Persian Verion

View:

709

Download:

Cites:

Information Journal Paper

Title

THE RELATIONSHIP BETWEEN DEVELOPING THALASSEMIA MAJOR AND DYSFUNCTION OF PANCREATIC ENDOCRINE AND EXOCRINE

Author(s)

Keywords

THALASSEMIAQ3

DIABETESQ2

PANCREAS FUNCTIONQ2

Abstract

Background and purpose: Frequent transfusions put the patients with THALASSEMIA at risk of iron overload complications which in turn can lead to failure in the function of organs such as heart and endocrine glands like liver and pancreas. Hence, in this study, the researchers are aiming at investigating the clinical and laboratory changes of pancreas in thalassemic patients.Materials and methods: This is a descriptive-analytic study in which 64 THALASSEMIA major patients were enrolled and divided in two groups of diabetic and non diabetic. In addition to some demographic and laboratory characteristics, serum amylase, trypsin, lipase, and fecal elastase were measured in both groups. Data were analyzed using t-test, Mann-Whitney, and Fisher’s exact tests.Results: Significant difference was observed in the mean of the last three serum ferritin level between the two groups (P<0.05). Findings showed that diabetic and non-diabetic patients didn’t have significant differences in the mean level of serum insulin and amylase, and fecal elastase, while significant differences were observed in FBS and 2h postprandial serum glucose (P<0.05). The analysis of the laboratory tests showed significant differences in serum lipase and fecal elastase in the two groups (P<0.05).Conclusion: DIABETES mellitus can lead to some adverse effects on pancreatic functions in the thalassemic children. The incidence of DIABETES in THALASSEMIA is more due to tissue resistance against insulin rather than pancreatic beta cells destruction and a decline in the serum insulin level.

Cites

No record.

References

No record.

Cite

APA: Copy

KARAMI, HASSAN, KOWSARIAN, MEHRNOOSH, KARAMI, HOSSAIN, KOWSARIAN, SEYED SHAHAB, MAHDAVI, MOHAMMAD REZA, DANESHMANDI, ZAHRA, KHADEMLOO, MOHAMMAD, & SHAHMOHAMMADI, SOHEILA. (2011). THE RELATIONSHIP BETWEEN DEVELOPING THALASSEMIA MAJOR AND DYSFUNCTION OF PANCREATIC ENDOCRINE AND EXOCRINE. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 21(83), 1-7. SID. https://sid.ir/paper/44387/en

Vancouver: Copy

KARAMI HASSAN, KOWSARIAN MEHRNOOSH, KARAMI HOSSAIN, KOWSARIAN SEYED SHAHAB, MAHDAVI MOHAMMAD REZA, DANESHMANDI ZAHRA, KHADEMLOO MOHAMMAD, SHAHMOHAMMADI SOHEILA. THE RELATIONSHIP BETWEEN DEVELOPING THALASSEMIA MAJOR AND DYSFUNCTION OF PANCREATIC ENDOCRINE AND EXOCRINE. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2011;21(83):1-7. Available from: https://sid.ir/paper/44387/en

IEEE: Copy

HASSAN KARAMI, MEHRNOOSH KOWSARIAN, HOSSAIN KARAMI, SEYED SHAHAB KOWSARIAN, MOHAMMAD REZA MAHDAVI, ZAHRA DANESHMANDI, MOHAMMAD KHADEMLOO, and SOHEILA SHAHMOHAMMADI, “THE RELATIONSHIP BETWEEN DEVELOPING THALASSEMIA MAJOR AND DYSFUNCTION OF PANCREATIC ENDOCRINE AND EXOCRINE,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 21, no. 83, pp. 1–7, 2011, [Online]. Available: https://sid.ir/paper/44387/en

Related Journal Papers