ASSOCIATION OF DEPRESSION AND ANXIETY WITH COGNITIVE FUNCTION IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME

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MEHRABADI SAIDE; JAHANIAN SADATMAHALLEH SHAHIDEH; KAZEMNEJAD ANOSHIRVAN

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Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2017 | Volume:27 | Issue:147 Page(s): 159-170

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Title

ASSOCIATION OF DEPRESSION AND ANXIETY WITH COGNITIVE FUNCTION IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME

Author(s)

MEHRABADI SAIDE | JAHANIAN SADATMAHALLEH SHAHIDEH | KAZEMNEJAD ANOSHIRVAN | Issue Writer Certificate

Keywords

COGNITIVE FUNCTIONQ3

DEPRESSIONQ2

ANXIETYQ2

POLYCYSTIC OVARY SYNDROMEQ2

Abstract

Background and purpose: POLYCYSTIC OVARY SYNDROME (PCOS) is the most common endocrine disorder (prevalence rate: 2.2-26%) in women of childbearing age. Symptoms of this condition are associated with psychological distress. Evaluation of COGNITIVE FUNCTION of PCOS patients has yielded discrepant results. Given that COGNITIVE FUNCTION of these patients might be affected by DEPRESSION and ANXIETY, this study aimed to evaluate the level of DEPRESSION and ANXIETY in this group of women, investigate their association with COGNITIVE FUNCTION, and compare the results with those of healthy women.Materials and methods: This case-control study was conducted in 53 patients with PCOS, selected using the Rotterdam diagnostic criteria, and 50 healthy women as control group. ANXIETY and DEPRESSION levels were evaluated by Beck’s ANXIETY and DEPRESSION inventories (second edition). Moreover, COGNITIVE FUNCTION of the participants was assessed using the Montreal Cognitive Assessment. Data analysis was performed in SPSS, version 21, using t-test, Chi-square and Pearson’s correlation coefficient.Results: In this study, the mean DEPRESSION score was significantly higher than that of the control group (20.35±9.82 vs. 14.46±8.40; P=0.001). In addition, a significant difference was observed between the two groups in terms of ANXIETY score, which was higher in the patient group (17.35±10.44 vs.12.40±9.65; P=0.01). Frequencies of severe DEPRESSION and ANXIETY in the patient group were 30.2% and 26.4%, respectively, while they were 6% and 12% in the control group, respectively; the difference between the two groups was statistically significant (P=0.007 and P=0.02, respectively). However, no significant association was noted between COGNITIVE FUNCTION and levels of DEPRESSION (r=-0.033, P=0.81) and ANXIETY (r=-0.15, P=0.26).Conclusion: Prevalence of DEPRESSION was found to be high in patients with PCOS. Despite many reports, we found no association between DEPRESSION and ANXIETY levels in PCOS patients and their COGNITIVE FUNCTION.

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APA: Copy

MEHRABADI, SAIDE, JAHANIAN SADATMAHALLEH, SHAHIDEH, & KAZEMNEJAD, ANOSHIRVAN. (2017). ASSOCIATION OF DEPRESSION AND ANXIETY WITH COGNITIVE FUNCTION IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 27(147), 159-170. SID. https://sid.ir/paper/44896/en

Vancouver: Copy

MEHRABADI SAIDE, JAHANIAN SADATMAHALLEH SHAHIDEH, KAZEMNEJAD ANOSHIRVAN. ASSOCIATION OF DEPRESSION AND ANXIETY WITH COGNITIVE FUNCTION IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;27(147):159-170. Available from: https://sid.ir/paper/44896/en

IEEE: Copy

SAIDE MEHRABADI, SHAHIDEH JAHANIAN SADATMAHALLEH, and ANOSHIRVAN KAZEMNEJAD, “ASSOCIATION OF DEPRESSION AND ANXIETY WITH COGNITIVE FUNCTION IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 147, pp. 159–170, 2017, [Online]. Available: https://sid.ir/paper/44896/en

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