EFFECT OF ACROPTILON REPENS L. AQUATIC EXTRACT ON HL-60 PROMYELOCYTIC LEUKEMIA CELL LINE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SOKOUTI ZAHRA; HOSEINI SEYYED MOHAMMAD; SHIRAVI ABDOLHOSSEIN; CHANGIZI REZA; MOSHREFI AMIRHOSSEIN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2017 | Volume:27 | Issue:147 Page(s): 41-47

Download Full-Text

Persian Verion

View:

762

Download:

Cites:

Information Journal Paper

Title

EFFECT OF ACROPTILON REPENS L. AQUATIC EXTRACT ON HL-60 PROMYELOCYTIC LEUKEMIA CELL LINE

Author(s)

Keywords

ACROPTILON REPENS L.Q2

CELL LINEQ2

EXTRACTQ1

HL-60Q3

LEUKEMIAQ2

Abstract

Background and purpose: Cancer is one of the leading causes of mortality worldwide. Acute promyelocytic LEUKEMIA, which is the most common type of blood cancer in adults, is the most prevalent type of acute LEUKEMIA. This type of cancer is characterized by uncontrolled proliferation, inhibited differentiation of immature myloied progenitors (promyelocytes), and accumulation of abnormal promyelocytes in the bone marrow. The aim of this study was to investigate the effects of ACROPTILON REPENS L. EXTRACT on the growth rate of the acute promyelocytic LEUKEMIA CELL LINE (HL-60).Materials and methods: This is an experimental study. The HL-60 cells are round with large nuclei. These cells were maintained at 37oC in 5% CO2 in RPMI-60 medium, supplemented with 10% fetal bovine serum, and 1% penicillin and streptomycin. The cytotoxic effects of Acroptilon repens EXTRACT on HL-60 CELL LINE was investigated using microculture tetrazolium test (MTT). To identify the cytotoxic doses, different dilutions of the Acroptilon repens EXTRACT were added to 96-well culture plate, each containing 20x4 cells. The treated cells were incubated for 24, 48, and 72 h, and then the viability of the cells was assessed using MTT.Results: According to the results, ACROPTILON REPENS L. EXTRACT has cytotoxic effects in concentrations of 1, 2, 4, 6, and 8 mg/ml.Conclusion: As the findings indicated, ACROPTILON REPENS L. EXTRACT could be effective in growth rate of acute promyelocytic LEUKEMIA CELL LINE (HL-60).

Cites

No record.

References

Cite

APA: Copy

SOKOUTI, ZAHRA, HOSEINI, SEYYED MOHAMMAD, SHIRAVI, ABDOLHOSSEIN, CHANGIZI, REZA, & MOSHREFI, AMIRHOSSEIN. (2017). EFFECT OF ACROPTILON REPENS L. AQUATIC EXTRACT ON HL-60 PROMYELOCYTIC LEUKEMIA CELL LINE. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 27(147), 41-47. SID. https://sid.ir/paper/44908/en

Vancouver: Copy

SOKOUTI ZAHRA, HOSEINI SEYYED MOHAMMAD, SHIRAVI ABDOLHOSSEIN, CHANGIZI REZA, MOSHREFI AMIRHOSSEIN. EFFECT OF ACROPTILON REPENS L. AQUATIC EXTRACT ON HL-60 PROMYELOCYTIC LEUKEMIA CELL LINE. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;27(147):41-47. Available from: https://sid.ir/paper/44908/en

IEEE: Copy

ZAHRA SOKOUTI, SEYYED MOHAMMAD HOSEINI, ABDOLHOSSEIN SHIRAVI, REZA CHANGIZI, and AMIRHOSSEIN MOSHREFI, “EFFECT OF ACROPTILON REPENS L. AQUATIC EXTRACT ON HL-60 PROMYELOCYTIC LEUKEMIA CELL LINE,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 147, pp. 41–47, 2017, [Online]. Available: https://sid.ir/paper/44908/en

Related Journal Papers