Factors Affecting the Progression of Retinopathy in Type 2 Diabetes

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Akbarpour Ensieh; YAZDANI CHARATI JAMSHID; Mohammadpour Tahamtan Rezaali; KASHI ZAHRA

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Journal: Journal of Mazandaran University of Medical Sciences Year:2019 | Volume:29 | Issue:172 Page(s): 110-120

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Title

Factors Affecting the Progression of Retinopathy in Type 2 Diabetes

Author(s)

Akbarpour Ensieh | YAZDANI CHARATI JAMSHID | Mohammadpour Tahamtan Rezaali | KASHI ZAHRA | Issue Writer Certificate

Keywords

diabetesQ2

retinopathyQ2

Weibull regressionQ1

accelerated failure timeQ1

Abstract

Background and purpose: The aim of this study was to identify the factors affecting the progression of retinopathy in patients with type 2 diabetes. Materials and methods: In this historical prospective cohort study, 728 patients with type 2 diabetes, attending Sari Tooba Clinic, were followed up for retinopathy. Data analysis was performed using accelerated failure time Weibull regression model in Stata V12. Results: The mean and median times until retinopathy progression was 17. 24 and 15 years, respectively. A total of 304 (41. 8%) patients developed retinopathy and 424 (58. 2%) were considered as right censoring observations. The incidence of retinopathy was 40. 5 per 1000 in person per year, and 5-year incidence rate from 5 to 25-year follow up were 7%, 15%, 24%, 41%, and 49%, respectively. The accelerated failure time Weibull regression showed age at the time of diagnosis of diabetes (P< 0. 001) and at first referral (P< 0. 001), nephropathy (P= 0. 122), hypertension (P< 0. 001), and hemoglobin A1c level (P= 0. 034) as the factors affecting the progression of retinopathy. Conclusion: Early diagnosis of diabetes and controlling hypertension and blood glucose as well as periodic examinations for early detection of nephropathy can delay the progression of retinopathy.

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APA: Copy

Akbarpour, Ensieh, YAZDANI CHARATI, JAMSHID, Mohammadpour Tahamtan, Rezaali, & KASHI, ZAHRA. (2019). Factors Affecting the Progression of Retinopathy in Type 2 Diabetes. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 29(172 ), 110-120. SID. https://sid.ir/paper/44951/en

Vancouver: Copy

Akbarpour Ensieh, YAZDANI CHARATI JAMSHID, Mohammadpour Tahamtan Rezaali, KASHI ZAHRA. Factors Affecting the Progression of Retinopathy in Type 2 Diabetes. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;29(172 ):110-120. Available from: https://sid.ir/paper/44951/en

IEEE: Copy

Ensieh Akbarpour, JAMSHID YAZDANI CHARATI, Rezaali Mohammadpour Tahamtan, and ZAHRA KASHI, “Factors Affecting the Progression of Retinopathy in Type 2 Diabetes,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 29, no. 172 , pp. 110–120, 2019, [Online]. Available: https://sid.ir/paper/44951/en

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