USING PARAMETRIC AND COX MODELS IN ANALYSIS OF FACTORS INFLUENCING THE DIAGNOSIS OF RETINOPATHY IN TYPE II DIABETES

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ASKARISHAHI MOHSEN; KESHAVARZI FATEMEH; AFKHAMI ARDAKANI MOHAMMAD; FALAHZADEH HOSSEIN

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Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2014 | Volume:24 | Issue:113 Page(s): 28-35

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Title

USING PARAMETRIC AND COX MODELS IN ANALYSIS OF FACTORS INFLUENCING THE DIAGNOSIS OF RETINOPATHY IN TYPE II DIABETES

Author(s)

ASKARISHAHI MOHSEN | KESHAVARZI FATEMEH | AFKHAMI ARDAKANI MOHAMMAD | FALAHZADEH HOSSEIN | Issue Writer Certificate

Keywords

DIABETESQ2

DIABETIC RETINOPATHYQ3

COX MODELQ2

PARAMETRIC MODELQ2

AKAIKE INFORMATION CRITERIONQ2

Abstract

Background and purpose: One of the major complications of DIABETES is retinopathy which is a highly specific vascular complication of type I and II DIABETES. This study aimed at investigating the factors influencing the diagnosis of retinopathy in patients with type II DIABETES using Cox, parametric, exponential, weibull, Log normal, and Log-logistic models and comparing their functions.Material and Methods: This prospective cohort study included 400 patients with type II DIABETES without retinopathy who were registered at Yazd DIABETES Research Center in 2008. They were followed up for diagnosis of retinopathy until February 2013. Significant variables in the univariate model for investigating the effective factors on diagnosis of retinopathy were entered in Cox multivariate and PARAMETRIC MODELs. The criterion to compare the performance of models was AKAIKE INFORMATION CRITERION. Data was then analyzed in R software and 0.05 was considered as the significance level.Results: The mean and median periods to diagnose retinopathy were 46 and 58 months. Among the patients 3% were diagnosed with retinopathy in less than one year and in 16% the diagnosis was made in less than two years.Conclusion: Some variables including anemia, taking aspirin, duration of DIABETES, and using insulin were amongst the main risk factors for diagnosis of retinopathy (P<0.05). According to AKAIKE INFORMATION CRITERION we found that COX MODEL best fits for determining factors influencing the diagnosis of retinopathy.

Cites

Factors Affecting the Progression of Retinopathy in Type 2 Diabetes

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APA: Copy

ASKARISHAHI, MOHSEN, KESHAVARZI, FATEMEH, AFKHAMI ARDAKANI, MOHAMMAD, & FALAHZADEH, HOSSEIN. (2014). USING PARAMETRIC AND COX MODELS IN ANALYSIS OF FACTORS INFLUENCING THE DIAGNOSIS OF RETINOPATHY IN TYPE II DIABETES. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 24(113), 28-35. SID. https://sid.ir/paper/45315/en

Vancouver: Copy

ASKARISHAHI MOHSEN, KESHAVARZI FATEMEH, AFKHAMI ARDAKANI MOHAMMAD, FALAHZADEH HOSSEIN. USING PARAMETRIC AND COX MODELS IN ANALYSIS OF FACTORS INFLUENCING THE DIAGNOSIS OF RETINOPATHY IN TYPE II DIABETES. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;24(113):28-35. Available from: https://sid.ir/paper/45315/en

IEEE: Copy

MOHSEN ASKARISHAHI, FATEMEH KESHAVARZI, MOHAMMAD AFKHAMI ARDAKANI, and HOSSEIN FALAHZADEH, “USING PARAMETRIC AND COX MODELS IN ANALYSIS OF FACTORS INFLUENCING THE DIAGNOSIS OF RETINOPATHY IN TYPE II DIABETES,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 113, pp. 28–35, 2014, [Online]. Available: https://sid.ir/paper/45315/en

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