CHANGES IN LIPID PROFILES AMONG PATIENTS WITH WITH CORONARYVASCULAR DISEASES TREATED WITH OMEGA3 AND VITAMIN E: ARANDOMIZED CONTROL CLINICAL TRIAL

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RAMEZANI ATENA; DJALALI MAHMOUD; YOSEFINEJAD ABBAS

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Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2018 | Volume:28 | Issue:162 Page(s): 1-11

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Title

CHANGES IN LIPID PROFILES AMONG PATIENTS WITH WITH CORONARYVASCULAR DISEASES TREATED WITH OMEGA3 AND VITAMIN E: ARANDOMIZED CONTROL CLINICAL TRIAL

Author(s)

RAMEZANI ATENA | DJALALI MAHMOUD | YOSEFINEJAD ABBAS | Issue Writer Certificate

Keywords

OMEGA 3Q1

VITAMIN EQ2

CORONARY VASCULAR DISEASESQ2

LIPID PROFILEQ1

TRIGLYCERIDEQ3

Abstract

Background and purpose: Omega-3 fatty acids and VITAMIN E have supportive effects againstcardiovascular diseases due to antioxidant properties, reduced thrombosis, lipid metabolism, andinflammation. The aim of this study was to investigate the effect of these supplements on LIPID PROFILEs incardiac patients. Materials and methods: A randomized, double-blind, placebo controlled trial was conductedin 62 male patients with CORONARY VASCULAR DISEASES (CVD). Participants were assigned into three studygroups; OE (OMEGA 3 fatty acids [EPA: 720 mg, DHA: 480 mg], n=22) plus VITAMIN E (400IU), OP(omega3 fatty acids [EPA: 720 mg, DHA: 480 mg], n=20), and PP (edible paraffin, n=20) for eightweeks. General information and 24-hour recall (at the beginning and the end of the study) and physicalactivity levels were recorded and serum LIPID PROFILEs were measured at the beginning and end of thestudy. Nutritionist IV was used to analyze dietary data and statistical data were analyzed using ANOVA, paired t-test, and Chi-square. Results: Omega-3 supplementation alone and plus VITAMIN E supplement, significantly decreasedserum TRIGLYCERIDE levels at the end of the study in all groups. According to ANCOVA, the meandifferences were also significant after removing the effects of confounding variables such as waist to hip(WHR), fat mass, free fat mass, BMI, and hsCRP (P=0. 008 and P=0. 003, respectively). Conclusion: This supplementation without affecting total cholesterol, LDL-C, and HDL-C levelsreduced TRIGLYCERIDE levels compared to those of the control group.

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APA: Copy

RAMEZANI, ATENA, DJALALI, MAHMOUD, & YOSEFINEJAD, ABBAS. (2018). CHANGES IN LIPID PROFILES AMONG PATIENTS WITH WITH CORONARYVASCULAR DISEASES TREATED WITH OMEGA3 AND VITAMIN E: ARANDOMIZED CONTROL CLINICAL TRIAL. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 28(162 ), 1-11. SID. https://sid.ir/paper/45048/en

Vancouver: Copy

RAMEZANI ATENA, DJALALI MAHMOUD, YOSEFINEJAD ABBAS. CHANGES IN LIPID PROFILES AMONG PATIENTS WITH WITH CORONARYVASCULAR DISEASES TREATED WITH OMEGA3 AND VITAMIN E: ARANDOMIZED CONTROL CLINICAL TRIAL. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;28(162 ):1-11. Available from: https://sid.ir/paper/45048/en

IEEE: Copy

ATENA RAMEZANI, MAHMOUD DJALALI, and ABBAS YOSEFINEJAD, “CHANGES IN LIPID PROFILES AMONG PATIENTS WITH WITH CORONARYVASCULAR DISEASES TREATED WITH OMEGA3 AND VITAMIN E: ARANDOMIZED CONTROL CLINICAL TRIAL,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 28, no. 162 , pp. 1–11, 2018, [Online]. Available: https://sid.ir/paper/45048/en

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