THE EFFECT OF LEVAMISOLE IN INHIBITION OF LEISHMANIA MAJOR IN BALB/C MICE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ZAHIR MOHAMMAD HASSAN; ARDESTANI S.K.; TAVASOLI N.; GHARAHGOUZLOU B.

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2004 | Volume:14 | Issue:44 Page(s): 37-44

Download Full-Text

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion

View:

1,000

Download:

Cites:

Information Journal Paper

Title

THE EFFECT OF LEVAMISOLE IN INHIBITION OF LEISHMANIA MAJOR IN BALB/C MICE

Author(s)

ZAHIR MOHAMMAD HASSAN | ARDESTANI S.K. | TAVASOLI N. | GHARAHGOUZLOU B. | Issue Writer Certificate

Keywords

LEISHMANIA MAJORQ3

LEVAMISOLEQ4

MACROPHAGEQ3

Abstract

Background and purpose: The infection of LEISHMANIA MAJOR in BALB/c mice can be visceralized if no treatment is administrated. The mamalian host cells are MACROPHAGEs that are responsible for ingestion and killing of the parasites.Since leishmaniasis is an immunosuppressive disease, it has been shown that LEVAMISOLE acts as an immuno-potentiator agent, attempts were made to study the effect of LEVAMISOLE on the course of visceral lieshmaniasis in BALB/c mice infected with L.major.Materials and methods: LEVAMISOLE is administrated i.p. (1, 2.5 and 5 mg/kg) 4hr before and 2 weeks after the challenge .The lesion size, delayed type hypersensitivity and parasite ingestion by MACROPHAGEs were assessed.Results: It was shown that LEVAMISOLE significantly reduced the lesion size and mortality in treated mice. In addition, it was demonstrated that parasite uptake was increased in mice receiving 2.5 mg/kg LEVAMISOLE Conclusion: Conclusively, in this study it was shown that LEVAMISOLE is able to control visceral leishmaniasis caused by L. major in BALB/c mice.

Cites

No record.

References

No record.

Cite

APA: Copy

ZAHIR, MOHAMMAD HASSAN, ARDESTANI, S.K., TAVASOLI, N., & GHARAHGOUZLOU, B.. (2004). THE EFFECT OF LEVAMISOLE IN INHIBITION OF LEISHMANIA MAJOR IN BALB/C MICE . JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 14(44), 37-44. SID. https://sid.ir/paper/45540/en

Vancouver: Copy

ZAHIR MOHAMMAD HASSAN, ARDESTANI S.K., TAVASOLI N., GHARAHGOUZLOU B.. THE EFFECT OF LEVAMISOLE IN INHIBITION OF LEISHMANIA MAJOR IN BALB/C MICE . JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2004;14(44):37-44. Available from: https://sid.ir/paper/45540/en

IEEE: Copy

MOHAMMAD HASSAN ZAHIR, S.K. ARDESTANI, N. TAVASOLI, and B. GHARAHGOUZLOU, “THE EFFECT OF LEVAMISOLE IN INHIBITION OF LEISHMANIA MAJOR IN BALB/C MICE ,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 14, no. 44, pp. 37–44, 2004, [Online]. Available: https://sid.ir/paper/45540/en

Related Journal Papers