The Effectiveness of Oral Corticosteroids in Improving Trigger Finger in Diabetic Patients

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NIKSOLAT FATEMEH; MOBINI MARYAM; HOSSEINIAN AMIRI AREF; Farzandi Sahar; MAJIDI HADI; AARABI MOHSEN

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Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2019 | Volume:28 | Issue:168 Page(s): 1-9

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Title

The Effectiveness of Oral Corticosteroids in Improving Trigger Finger in Diabetic Patients

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Keywords

trigger fingerQ1

oral corticosteroidsQ1

diabetes mellitusQ2

Abstract

Background and purpose: Evidence suggest high prevalence of trigger finger (TF) in diabetic patients. Corticosteroid injection in the area of tendon sheath thickening is the first-line treatment of choice for TF. However, some studies indicated low efficacy of this method in diabetic patients. This study aimed at investigating the effectiveness of oral corticosteroids in diabetic patients with TF. Materials and methods In a clinical trial, 50 diabetic patients with trigger finger (n=106 digits) enrolled. The patients were treated with oral prednisolone 5 mg, three times a day for 2 weeks. They were then followed up based on Quinnell grading at 3 and 6 weeks, and 3 months. Data analysis was done in SPSS V17 applying Repeated measures ANOVA. Results At the end of the three-month follow-up, 84 fingers (79. 3%) of patients who took oral prednisolone improved. The reduction of Quinnell grading was significant after medication (p<0. 001). Positive correlation was observed between symptoms duration and disease severity at third month (r=0. 37, p<0. 0001). In addition, there were positive correlations between the number of fingers affected and diabetes mellitus duration (r=0. 425, p=0. 002), HbA1C (r=0. 319, p=0. 024), and 2HPP (r=0. 29, p=0. 041). Conclusion Current study showed no local side effects of corticosteroids in patients receiving oral prednisolone. Therefore, it could be suggested as an influential treatment for trigger finger in diabetic patients, especially those with less than 6 months onset of symptoms, normal blood glucose control, less severity of the symptoms, and higher number of involved fingers.

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APA: Copy

NIKSOLAT, FATEMEH, MOBINI, MARYAM, HOSSEINIAN AMIRI, AREF, Farzandi, Sahar, MAJIDI, HADI, & AARABI, MOHSEN. (2019). The Effectiveness of Oral Corticosteroids in Improving Trigger Finger in Diabetic Patients. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 28(168 ), 1-9. SID. https://sid.ir/paper/45601/en

Vancouver: Copy

NIKSOLAT FATEMEH, MOBINI MARYAM, HOSSEINIAN AMIRI AREF, Farzandi Sahar, MAJIDI HADI, AARABI MOHSEN. The Effectiveness of Oral Corticosteroids in Improving Trigger Finger in Diabetic Patients. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;28(168 ):1-9. Available from: https://sid.ir/paper/45601/en

IEEE: Copy

FATEMEH NIKSOLAT, MARYAM MOBINI, AREF HOSSEINIAN AMIRI, Sahar Farzandi, HADI MAJIDI, and MOHSEN AARABI, “The Effectiveness of Oral Corticosteroids in Improving Trigger Finger in Diabetic Patients,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 28, no. 168 , pp. 1–9, 2019, [Online]. Available: https://sid.ir/paper/45601/en

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