THE EFFECT OF THE ADMINISTRATION OF CORTICOSTEROID ON THE TREATMENT OF PATIENTS WITH BRUCELLOSIS

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KARAMI A.; MOBAIEN A.R.; JOZPANAHI M.; SAROKHANI M.

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Journal Paper

Paper Information

Journal: Journal of Arak University Medical Sciences Year:2012 | Volume:14 | Issue:6 (SUPPL 3) Page(s): 78-84

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Title

THE EFFECT OF THE ADMINISTRATION OF CORTICOSTEROID ON THE TREATMENT OF PATIENTS WITH BRUCELLOSIS

Author(s)

KARAMI A. | MOBAIEN A.R. | JOZPANAHI M. | SAROKHANI M. | Issue Writer Certificate

Keywords

BRUCELLOSISQ2

CORTICOSTEROIDQ2

OUTCOMEQ2

Abstract

Background: BRUCELLOSIS is an endemic disease in Iran and its treatment is a medical problem. This study was performed to observe the influence of the administration of CORTICOSTEROID on symptomatology of subjects with acute, subacute, and chronic BRUCELLOSIS.Materials and Methods: In this randomized controlled trial, 48 patients with BRUCELLOSIS were randomly assigned to two groups. The first group (N=30) received the standard regimen plus dexamethasone (4 mg t.d.s for 5 days) and the second group (N=17) received only the standard regimen. The results of CORTICOSTEROID administration were evaluated according to such factors as clinical status of the patient, duration of hospital stay, duration of illness, pain score, and use of analgesics. The results were analyzed by Chi-square test, Fisher’s exact test, independent sample t-test, and Mann-Whitney test.Results: No significant differences were seen in the mean of hospital stay, duration of illness, and use of oral and injectable analgesics between the two groups (P<0.05). Also, there was not a significant difference in mean pain score reduction between groups 1 and 2 (P<0.05).Conclusion: Noticing the findings of this study, CORTICOSTEROID does not seem to alter the clinical course of BRUCELLOSIS significantly. Nevertheless, further controlled clinical trials with larger sample sizes are recommended.

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APA: Copy

KARAMI, A., MOBAIEN, A.R., JOZPANAHI, M., & SAROKHANI, M.. (2012). THE EFFECT OF THE ADMINISTRATION OF CORTICOSTEROID ON THE TREATMENT OF PATIENTS WITH BRUCELLOSIS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), 14(6 (SUPPL 3)), 78-84. SID. https://sid.ir/paper/68959/en

Vancouver: Copy

KARAMI A., MOBAIEN A.R., JOZPANAHI M., SAROKHANI M.. THE EFFECT OF THE ADMINISTRATION OF CORTICOSTEROID ON THE TREATMENT OF PATIENTS WITH BRUCELLOSIS. ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ)[Internet]. 2012;14(6 (SUPPL 3)):78-84. Available from: https://sid.ir/paper/68959/en

IEEE: Copy

A. KARAMI, A.R. MOBAIEN, M. JOZPANAHI, and M. SAROKHANI, “THE EFFECT OF THE ADMINISTRATION OF CORTICOSTEROID ON THE TREATMENT OF PATIENTS WITH BRUCELLOSIS,” ARAK MEDICAL UNIVERSITY JOURNAL (AMUJ), vol. 14, no. 6 (SUPPL 3), pp. 78–84, 2012, [Online]. Available: https://sid.ir/paper/68959/en

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